A nurse is assessing a patient with suspected SIADH.
Which findings support this diagnosis? (Select all that apply)
Hyponatremia.
Hypernatremia.
Concentrated urine.
Polyuria.
Low serum osmolality.
Correct Answer : A,C,E
Choice A rationale
Hyponatremia occurs in SIADH due to the excessive secretion of antidiuretic hormone, which causes the kidneys to reabsorb an inappropriate amount of free water. This water retention dilutes the concentration of sodium in the extracellular fluid, leading to serum sodium levels falling below the normal range of 135 to 145 mEq/L. The resulting dilutional hyponatremia can lead to cellular edema and significant neurological complications if the water intake is not strictly restricted to manage the imbalance.
Choice B rationale
Hypernatremia is not associated with SIADH because the primary pathophysiology involves water retention rather than water loss or sodium excess. Hypernatremia, defined as a serum sodium level greater than 145 mEq/L, is typically seen in conditions like diabetes insipidus where there is a deficiency of antidiuretic hormone or a lack of renal response to it. In SIADH, the body retains too much water, which consistently lowers the sodium concentration through dilution rather than raising it through dehydration.
Choice C rationale
Concentrated urine is a hallmark of SIADH because the high levels of circulating antidiuretic hormone act on the renal collecting ducts to increase water permeability. This results in maximum water reabsorption back into the systemic circulation, leaving very little water to be excreted. Consequently, the urine produced is highly concentrated with a high specific gravity, typically exceeding 1.030, and a high urine osmolality, reflecting the body's inability to excrete excess water despite low serum osmolality levels.
Choice D rationale
Polyuria is the excretion of large volumes of dilute urine, which is the opposite of what occurs in SIADH. Patients with SIADH actually experience oliguria because the kidneys are reabsorbing almost all filtered water under the influence of excessive antidiuretic hormone. Polyuria is a clinical manifestation of diabetes insipidus or osmotic diuresis, where the kidneys fail to concentrate urine. In SIADH, the volume of urine output is significantly decreased while the concentration of the urine remains abnormally high.
Choice E rationale
Low serum osmolality is a direct result of the excessive water retention seen in SIADH. As the body reabsorbs free water in the distal tubules and collecting ducts, the blood becomes diluted, lowering the concentration of particles. Normal serum osmolality ranges from 275 to 295 mOsm/kg. In SIADH, this value drops below 275 mOsm/kg. This hypoosmolar state occurs simultaneously with the production of concentrated urine, which is a diagnostic indicator that the ADH secretion is inappropriate.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Visceral pain originates from the internal organs within the thorax, abdomen, or pelvis. The nerves supplying these organs are fewer and less specialized than those in the skin. Consequently, visceral pain is often described as dull, aching, or squeezing and is poorly localized, making it difficult for the patient to point to a specific spot. It is frequently associated with autonomic responses such as nausea or changes in heart rate and blood pressure due to organ distension.
Choice B rationale
Neuropathic pain results from direct damage to or dysfunction of the nervous system itself rather than tissue injury. It is typically described by patients as burning, tingling, shooting, or electric-like sensations. Unlike the dull discomfort of visceral pain, neuropathic pain often follows a specific nerve distribution and can be associated with hypersensitivity to touch. It is common in conditions like diabetic neuropathy, shingles, or nerve compression syndromes where the signaling process is pathologically altered.
Choice C rationale
Referred pain is pain perceived at a location other than the site of the actual painful stimulus. This happens because various visceral organs and skin areas share common sensory pathways in the spinal cord. A classic example is shoulder pain during a myocardial infarction or gallbladder disease. While referred pain can be poorly localized, the question specifically asks about the classification of the nature of the abdominal discomfort itself rather than its secondary location in a distant area.
Choice D rationale
Somatic pain arises from the skin, muscles, joints, or bones. It is generally well-localized because these tissues are densely populated with sensory receptors. Patients can usually point exactly to the source of the pain, which is often described as sharp, throbbing, or stabbing. Because the abdominal discomfort mentioned in the scenario is dull and difficult to pinpoint, it does not fit the characteristic description of somatic pain, which is much more precise and intense.
Correct Answer is A
Explanation
Choice A rationale
Administering 2 tablets is the correct action because the ordered dose is 500 mg and each available tablet contains 250 mg. By providing two of these tablets, the nurse delivers the exact amount prescribed. This calculation is a basic nursing competency used to ensure medication safety. Giving the correct number of tablets prevents underdosing, which would result in subtherapeutic levels of the medication, and overdosing, which could lead to toxicity or adverse reactions for the patient.
Choice B rationale
Administering 1 tablet would only provide 250 mg of the medication, which is exactly half of the 500 mg dose that was ordered by the healthcare provider. Providing only one tablet would result in a medication error categorized as underdosing. This would fail to meet the therapeutic needs of the patient and could lead to a worsening of the condition being treated, as the drug concentration in the bloodstream would not reach the necessary level for effectiveness.
Choice C rationale
Administering 1.5 tablets would provide a total dose of 375 mg, as 250 mg multiplied by 1.5 equals 375 mg. This amount is still 125 mg short of the required 500 mg dose. While closer than a single tablet, it remains an incorrect dosage that would not fulfill the prescriber's order. Nursing practice requires precise calculation to ensure that the patient receives the specific amount of active ingredient necessary to produce the desired physiological response without error.
Choice D rationale
Administering 0.5 tablets would only provide 125 mg of the medication, which is significantly less than the 500 mg dose required for the patient. Such a small amount would be entirely insufficient for treating the patient's condition. In clinical practice, the nurse must always verify the dose on hand against the dose ordered. Using a half tablet in this scenario would be a clear mathematical error and a violation of the rights of medication administration.
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