A nurse is caring for a client in an antepartum clinic following a maternal serum alpha-fetoprotein screening.
The nurse should recognize that an elevated alpha-fetoprotein level is suggestive of which of the following?
Neural tube defects.
Phenylketonuria.
Trisomy 21.
Hemophilia.
The Correct Answer is A
Choice A rationale
An elevated maternal serum alpha-fetoprotein (MSAFP) level is a significant biomarker that can suggest an increased risk of open neural tube defects (NTDs), such as spina bifida or anencephaly. Alpha-fetoprotein is a protein produced by the fetal liver and yolk sac; in cases of open NTDs, larger amounts leak into the amniotic fluid and subsequently cross into the maternal bloodstream, resulting in higher MSAFP levels. Further diagnostic tests like ultrasound or amniocentesis are typically recommended to confirm the diagnosis.
Choice B rationale
Phenylketonuria (PKU) is an inherited metabolic disorder characterized by the inability to metabolize the amino acid phenylalanine. This condition is diagnosed through newborn screening tests that measure phenylalanine levels in the blood, not by maternal serum alpha-fetoprotein screening. MSAFP is not a marker for metabolic disorders like PKU, as it is primarily indicative of fetal structural anomalies, particularly neural tube defects.
Choice C rationale
Trisomy 21, also known as Down syndrome, is a chromosomal disorder caused by the presence of an extra copy of chromosome 21. While MSAFP is part of the "triple screen" or "quad screen" used for aneuploidy screening, an elevated MSAFP level alone is typically associated with neural tube defects. In cases of Trisomy 21, MSAFP levels are usually *lower* than normal, in conjunction with altered levels of other markers like human chorionic gonadotropin (hCG) and unconjugated estriol.
Choice D rationale
Hemophilia is a genetic bleeding disorder caused by a deficiency in specific clotting factors, primarily factors VIII or IX. This condition is inherited in an X-linked recessive pattern and is diagnosed through specialized blood tests that measure clotting factor activity. Maternal serum alpha-fetoprotein screening is not used to detect hemophilia, as it is a marker for fetal structural integrity, particularly concerning neural tube and abdominal wall defects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Applying witch hazel compresses (often in the form of Tucks pads) is an effective and common intervention for episiotomy discomfort. Witch hazel possesses astringent and anti-inflammatory properties that can reduce swelling, soothe irritation, and promote healing of the perineal tissues, providing significant pain relief for the postpartum client.
Choice B rationale
Administering aspirin is generally contraindicated in the immediate postpartum period, especially if there is any risk of bleeding or if the client is breastfeeding. Aspirin can inhibit platelet aggregation, increasing the risk of postpartum hemorrhage. Safer analgesics, such as NSAIDs like ibuprofen, or acetaminophen, are preferred for pain relief.
Choice C rationale
Having the client use a warm pack is generally not recommended for immediate episiotomy discomfort. While warmth can be soothing, a warm pack can increase blood flow to the area, potentially increasing swelling and discomfort or exacerbating any bleeding in the immediate postpartum period. Cold applications are typically preferred initially.
Choice D rationale
Instructing the client to sit on a soft pillow may provide some comfort by distributing pressure, but it does not directly address the underlying pain and inflammation from the episiotomy. While it can be a supportive measure, it is not as therapeutically effective as direct interventions like cold packs, witch hazel, or appropriate analgesia. .
Correct Answer is D
Explanation
Choice A rationale
Combined estrogen-progestin contraceptive pills typically regulate the menstrual cycle and can often lead to shorter, lighter periods, or even amenorrhea in some individuals, due to the suppression of endometrial proliferation. The synthetic hormones, estrogen and progestin, stabilize the endometrium, preventing excessive build-up and subsequent heavy bleeding.
Choice B rationale
Medroxyprogesterone acetate (Depo-Provera) is an injectable contraceptive that provides long-acting contraception. It is administered intramuscularly or subcutaneously, but the typical administration frequency is once every 3 months (13 weeks), not once per month. This extended duration of action is due to the sustained release of the progestin.
Choice C rationale
Diaphragms are reusable barrier contraceptive devices. While a single diaphragm can be used for several years, it typically needs to be replaced every 1 to 2 years, or sooner if there is a significant weight change (gain or loss of 10-15 pounds), or after pregnancy, to ensure proper fit and contraceptive efficacy.
Choice D rationale
Oral contraceptives, particularly those containing estrogen and progestin, have been shown to significantly reduce the risk of endometrial cancer. This protective effect is primarily attributed to the progestin component, which counteracts the proliferative effects of estrogen on the endometrium, thereby preventing hyperplasia and subsequent malignant transformation.
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