A nurse is caring for a client who is receiving phenytoin. Which of the following conditions should the nurse identify as an indication for this medication?
Status asthmaticus
Status epilepticus
Kidney transplant
Endocarditis
The Correct Answer is B
Phenytoin is a primary anticonvulsant utilized for the management of generalized tonic-clonic seizures and complex partial seizures. It works by blocking voltage-gated sodium channels, thereby preventing the repetitive firing of neuronal action potentials that characterize seizure activity. Its role in neurological stabilization is well-established, though it requires diligent monitoring of serum drug levels to ensure therapeutic efficacy.
Rationale:
A. Status asthmaticus is an acute, severe asthma exacerbation that does not respond to standard bronchodilator therapy and requires corticosteroids or oxygen. Phenytoin has no pharmacological role in the respiratory system or the treatment of bronchospasm. This condition is a medical emergency focused on ventilation and airway management rather than the control of neuronal electrical activity.
B. Status epilepticus is a life-threatening state of persistent seizure activity where phenytoin is frequently used as a secondary agent for long-term seizure control. Following the initial administration of benzodiazepines to stop the acute seizure, phenytoin provides the sustained neuronal stabilization needed to prevent recurrence. It is a cornerstone of emergency neurological protocols designed to protect the brain from metabolic exhaustion.
C. A kidney transplant requires the lifelong administration of immunosuppressant medications, such as cyclosporine or tacrolimus, to prevent organ rejection. Phenytoin is not an immunosuppressant and actually has significant drug interactions that could lower the levels of transplant medications. Using phenytoin in this context would be inappropriate and potentially detrimental to the survival of the transplanted organ.
D. Endocarditis is a microbial infection of the heart valves or endocardium that necessitates prolonged courses of high-dose intravenous antibiotics. Phenytoin does not possess antimicrobial properties and cannot treat the underlying infection in endocarditis. While a patient with endocarditis might have a seizure due to an embolic stroke, the indication for phenytoin remains seizure management, not the heart condition.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Safe medical documentation requires the use of standardized terminologyand the avoidance of dangerous abbreviations to prevent medication errors. The Joint Commission maintains a "Do Not Use" list, which prohibits notations that are easily misinterpreted, such as trailing zeros or missing leading zeros.
Rationale:
A.This entry is incorrect because it uses the abbreviation "QD" for daily, which is on the prohibited list as it can be mistaken for "QID" (four times daily). Additionally, it fails to include the unit of measurement "mg" after the dosage, which is a critical safety component. Standardized documentation requires writing out the word "daily" and including full units to ensure there is no ambiguity in the medical record.
B.This is the correct entry because it follows all safety protocols, including the use of a leading zero (0.25 mg) and writing out "daily" and "by mouth." It also correctly documents that it was a verbal order (VO) and identifies both the prescribing provider and the receiving nurse. This level of detail ensures the order is legally sound and minimizes the risk of a ten-fold dosing error or route confusion.
C.This entry is unsafe because it lacks a leading zero (.25 mg), which could result in the patient receiving 25 mg instead of 0.25 mg if the decimal point is missed. Such a massive overdose of digoxin would likely be fatal due to its narrow therapeutic index and cardiac toxicity. Furthermore, it fails to document that the order was a verbal order, which is necessary for legal and clinical accountability.
D.Similar to choice C, this entry is incorrect due to the omission of the leading zero before the decimal point (.25 mg). While it correctly uses "VO" and "daily," the lack of a leading zero is a high-risk charting error that directly violates patient safety standards. Proper notation must always place a zero before a decimal to highlight the fractional nature of the dose to all clinical staff.
Correct Answer is D
Explanation
Salicylism is a toxic condition resulting from excessive salicylateaccumulation, often characterized by acid-base disturbances and neurological changes. It disrupts metabolicprocesses and affects the vestibulocochlear nerve, leading to distinct sensory impairments. Prompt recognition of early toxicity is vital to prevent severe respiratory alkalosisor metabolic acidosis.
Rationale:
A.Diplopia, or double vision, is not a hallmark sign of early salicylate toxicity or salicylism. While severe poisoning can eventually lead to central nervous system depression and visual disturbances, it is not the primary indicator used for clinical screening. The nurse should look for signs more specific to the Eighth cranial nerve and acid-base status when assessing for aspirin toxicity.
B.Joint pain is an indication for taking aspirin rather than a sign of its toxicity. Aspirin is frequently used to treat inflammatory conditions like rheumatoid arthritis or osteoarthritis due to its inhibition of cyclooxygenase. If a client continues to experience joint pain, it suggests the dosage is therapeutic or perhaps insufficient, rather than indicating an overdose or salicylism.
C.Facial edema is more indicative of a type I hypersensitivity reaction or angioedema rather than chronic salicylate toxicity. While a patient can be allergic to aspirin, this finding represents an acute immunological response rather than the metabolic syndrome of salicylism. Salicylism specifically targets the auditory system and metabolic pathways rather than causing localized soft tissue swelling.
D.Tinnitus, described as a ringing or buzzing in the ears, is the most common early clinical manifestation of salicylism. It occurs because high levels of aspirin are toxic to the hair cells within the cochlea and affect the acoustic nerve. The nurse must instruct the client that the onset of tinnitus requires immediate cessation of the medication and a medical evaluation to prevent further toxicity.
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