A nurse is caring for a client with acute myeloid leukemia (AML) who is having hematopoietic stem cell transplantation (HSCT) with radiation therapy. In which complication do the donor's lymphocytes recognize the patient's body as foreign and set up reactions to attack the foreign host?
Graft-versus-host disease
Bone marrow depression
Acute respiratory distress syndrome
Remission
The Correct Answer is A
A. Graft-versus-host disease (GVHD): GVHD is a complication that occurs after hematopoietic stem cell transplantation (HSCT), where the donor's immune cells (lymphocytes) recognize the recipient’s body as foreign and attack the recipient's tissues. This is a common concern in HSCT, particularly with allogeneic transplants.
B. Bone marrow depression: Bone marrow depression is a common side effect of both chemotherapy and radiation therapy, but it does not involve the donor’s immune cells attacking the recipient’s body. It refers to the reduced ability of the bone marrow to produce blood cells.
C. Acute respiratory distress syndrome (ARDS): ARDS is a severe lung condition that can result from various causes such as trauma, infection, or inflammation, but it is not specifically related to GVHD or HSCT.
D. Remission: Remission refers to the reduction or disappearance of disease symptoms, especially in cancer. It is not a complication of HSCT, and it does not involve the donor’s immune cells attacking the patient’s body.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. "I understand what you mean, you can never be sure if the blood is tainted." This response would be inappropriate as it may increase the patient's anxiety and perpetuate fear about the transfusion. It does not provide accurate information about the safety of blood transfusions.
B. "I understand your concern. The blood is screened very carefully for different viruses as well as HIV." This response acknowledges the patient's concern while providing accurate and reassuring information. Blood donations are rigorously screened for HIV and other infectious diseases to ensure safety.
C. "If you don't have the blood transfusions, you may not make it through this episode of bleeding." While this statement is true, it focuses on the negative consequence without addressing the patient's fear. It also lacks a supportive and informative approach to the patient's concern about HIV.
D. "No one has gotten HIV from blood in a long time. You have to have the transfusion." This is dismissive and does not adequately address the patient's concern or provide accurate information about the safety measures in place for blood transfusions. It also pressures the patient into a decision without educating them.
Correct Answer is B
Explanation
A. Have the client use the early-morning hours for exercise and activity: Clients with COPD may experience morning respiratory symptoms, so it is better to encourage exercise and activity when they feel most comfortable not strictly early morning.
B. Instruct the client to use pursed-lip breathing: Pursed-lip breathing helps clients with COPD slow their breathing, increase lung volume, and improve oxygenation. It is an effective technique to reduce the feeling of breathlessness and improve airflow.
C. Restrict the client's fluid intake to less than 2 L/day: Fluid intake should not be restricted in COPD unless there are specific contraindications, such as heart failure. Adequate hydration is important to thin secretions and make them easier to expectorate.
D. Provide the client with a low-protein diet: Clients with COPD may have higher energy needs and require adequate protein intake to prevent muscle wasting and maintain strength for respiratory function. A balanced, nutrient-dense diet is ideal.
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