A nurse is educating a client who has inflammatory bowel disease (IBD) about managing their condition with corticosteroids. Which of the following statements by the nurse accurately describes the primary action of corticosteroids in treating IBD
Corticosteroids increase the immune response and enhance inflammation, aggravating symptoms
Corticosteroids balance electrolytes and water in the body improving gut motility in IBD
Corticosteroids suppress the immune system and reduce inflammation, helping to improve symptoms in IBD.
Corticosteroids increase the production of proinflammatory cytokines, improving symptoms in IBD.
The Correct Answer is C
A. Corticosteroids increase the immune response and enhance inflammation, aggravating symptoms: Corticosteroids inhibit multiple inflammatory pathways rather than stimulating them. Increasing immune activity would worsen mucosal inflammation in inflammatory bowel disease. This mechanism is opposite to the therapeutic goal of corticosteroid therapy.
B. Corticosteroids balance electrolytes and water in the body, improving gut motility: Although corticosteroids can affect fluid and electrolyte balance as a side effect, this is not the therapeutic mechanism in inflammatory bowel disease. Symptom relief occurs through anti-inflammatory effects on the intestinal mucosa.
C. Corticosteroids suppress the immune system and reduce inflammation, helping to improve symptoms in inflammatory bowel disease: Corticosteroids decrease leukocyte migration and inhibit the release of inflammatory mediators in the intestinal wall. Reduced inflammation leads to decreased edema, ulceration, and mucosal damage. This mechanism helps control disease flares and improve clinical symptoms.
D. Corticosteroids increase the production of proinflammatory cytokines, improving symptoms in inflammatory bowel disease: Corticosteroids reduce the production of proinflammatory cytokines such as interleukins and tumor necrosis factor. Increasing cytokine production would intensify intestinal inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Ask the client which medication they prefer to take:Asking the client to choose between duplicated medications places a clinical decision beyond the client’s scope. Medication selection and adjustment require prescriber evaluation of indication, dose, and risk for adverse effects. Client input is valuable but cannot replace provider decision-making.
B. Discontinue one of the medications immediately:Stopping a medication without a prescription exceeds the nurse’s scope of practice. Abrupt discontinuation may cause therapeutic failure or adverse effects, depending on the drug class. Medication changes must be authorized by the prescribing provider.
C. Continue with the current medications as prescribed:Continuing duplicated medications increases the risk of toxicity, overdose, or compounded adverse effects. Medication reconciliation is intended to identify and resolve discrepancies before harm occurs. Ignoring duplication defeats the purpose of the safety check.
D. Notify the healthcare provider for further instructions:Notifying the healthcare provider allows clarification of the intended regimen and prevention of medication-related harm. The provider can discontinue, adjust, or substitute medications as appropriate. This action supports safe medication management and interprofessional communication.
Correct Answer is B
Explanation
A. Give the medication only when the client requests:Administering medication on the client’s request may not align with the timing needed for accurate peak and trough levels. This approach can compromise therapeutic monitoring and safety.
B. Coordinate administration with laboratory timing for accurate peak and trough levels:Peak and trough levels measure the highest and lowest concentrations of a medication in the blood to ensure efficacy and prevent toxicity. Proper coordination of dosing and lab draws is essential for accurate monitoring and safe medication management.
C. Administer the medication at any time:Giving the medication without regard to timing can result in inaccurate peak and trough measurements, increasing the risk of underdosing or toxicity. Timing is critical for medications requiring serum level monitoring.
D. Ensure the client consumes a high-fat meal with the medication:Food content may affect absorption of some medications, but a high-fat meal is not a universal requirement and does not replace correct timing for peak and trough monitoring. It is not the primary consideration in this scenario.
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