A nurse is planning care for a client who is withdrawing from alcohol. Which of the following medications should the nurse plan to administer during the acute phase of alcohol withdrawal?
Varenicline
Diazepam
Disulfiram
Acamprosate
The Correct Answer is B
Choice A reason: Varenicline is a partial nicotinic acetylcholine receptor agonist used for smoking cessation. It reduces cravings and withdrawal symptoms associated with nicotine dependence but has no role in managing acute alcohol withdrawal. Alcohol withdrawal involves hyperexcitability of the central nervous system due to the sudden absence of GABAergic stimulation, and Varenicline does not address this pathophysiology.
Choice B reason: Diazepam, a benzodiazepine, is the drug of choice for acute alcohol withdrawal. Benzodiazepines enhance GABA activity, counteracting the excitatory state caused by alcohol cessation. They reduce the risk of seizures, delirium tremens, and autonomic instability. Diazepam’s long half-life provides smoother withdrawal coverage and reduces rebound symptoms. Clinically, it is administered under close monitoring to titrate sedation and prevent complications.
Choice C reason: Disulfiram is an aversive agent used for long-term alcohol abstinence. It inhibits aldehyde dehydrogenase, causing accumulation of acetaldehyde when alcohol is consumed, leading to unpleasant symptoms such as flushing, nausea, and palpitations. However, it is contraindicated during acute withdrawal because it does not relieve withdrawal symptoms and may worsen the client’s condition if alcohol is ingested.
Choice D reason: Acamprosate is used for maintaining abstinence after detoxification. It modulates glutamatergic neurotransmission, reducing cravings and preventing relapse. However, it is not effective in treating acute withdrawal symptoms such as tremors, seizures, or delirium. Its role is supportive in long-term recovery, not immediate stabilization.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Sleeping only 4 hours is common during mania and contributes to exhaustion, but it is not immediately life-threatening.
Choice B reason: Refusing to shower reflects poor self-care, which is expected in mania, but it does not pose an acute medical risk.
Choice C reason: Eating half a snack shows reduced intake but is not as urgent as fluid refusal.
Choice D reason: Refusing fluids is the priority because dehydration can quickly lead to severe complications such as electrolyte imbalance, cardiac dysrhythmias, and renal impairment. This requires immediate intervention.
Correct Answer is {"A":{"answers":"A"},"B":{"answers":"A"},"C":{"answers":"A"},"D":{"answers":"A"},"E":{"answers":"B"}}
Explanation
Rationale for PET scan: A PET scan of the head is anticipated because the client is showing progressive cognitive decline, memory loss, and disorientation. Neuroimaging is appropriate to rule out structural or metabolic causes such as stroke, tumors, or neurodegenerative disease. This helps differentiate dementia from other neurological conditions.
Rationale for physical examination: A physical exam is anticipated because it provides a baseline assessment of the client’s overall health, identifies comorbid conditions, and evaluates neurological status. Physical findings can guide further diagnostic testing and management.
Rationale for MMSE: Administering the Mini Mental State Examination is anticipated because it is a standardized tool used to assess cognitive function, memory, orientation, and problem-solving ability. Given the client’s symptoms of forgetfulness, disorientation, and difficulty with daily tasks, the MMSE will help quantify cognitive impairment and track progression.
Rationale for medication review: Reviewing all prescribed and over-the-counter medications is anticipated because certain drugs can contribute to confusion, memory loss, or delirium. Polypharmacy and inappropriate medication use are common in older adults and can mimic or worsen dementia symptoms. Identifying and adjusting medications is a critical step in care.
Rationale for inpatient behavioral health admission: Admission to a behavioral health unit is not indicated at this stage. The client’s symptoms are consistent with progressive dementia rather than an acute psychiatric crisis. The focus should be on diagnostic evaluation, outpatient management, and support rather than psychiatric hospitalization
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