A nurse is preparing to administer cefazolin 500 mg IM every 8 hr. Available is cefazolin 1 g vial. The package insert instructs adding sterile water 2.5 mL to yield cefazolin 330 mg/mL. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Answer and Explanation

The Correct Answer is ["1.5"]

First, we need to calculate the amount of cefazolin 500 mg in milligrams per milliliter (mg/mL) using the information provided:

Cefazolin concentration after reconstitution = 330 mg/mL Amount of cefazolin needed per dose = 500 mg

Now we can calculate the volume (mL) required for the dose:

Volume (mL) = Amount of cefazolin needed per dose / Cefazolin concentration after reconstitution

Volume (mL) = 500 mg / 330 mg/mL ≈ 1.52 mL

Rounded to the nearest tenth, the nurse should administer approximately 1.5 mL of cefazolin per dose.

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Correct Answer is ["0.71"]

Explanation

To calculate how many milliliters (mL) of the reconstituted medication to administer, you need to determine the desired dose and then divide it by the concentration of the reconstituted solution.

The label indicates that each vial, when reconstituted, contains ceftriaxone 350 mg/mL.

The desired dose is 250 mg.

So, you can use the following formula:

Volume to administer (mL) = Desired dose (mg) / Concentration of the reconstituted solution (mg/mL)

Volume to administer (mL) = 250 mg / 350 mg/mL

Volume to administer (mL) = 0.7143 mL (rounded to the nearest hundredth)

Therefore, the nurse should administer approximately 0.71 mL of the reconstituted ceftriaxone solution.

A. Store the medication at room temperature following reconstitution B. Use 0.9% sodium chloride solution as a diluent C. Discard any remaining medication after 10 days D. Roll the vial gently in hands to mix the medication

Correct Answer is C

Explanation

a. Store the medication at room temperature following reconstitution: This option is incorrect. While it provides information about the storage of the medication after reconstitution, it doesn't pertain to the reconstitution process itself. Storage information is essential but not part of the reconstitution process.

b. Use 0.9% sodium chloride solution as a diluent: This option is incorrect. The label instructions mention adding water for reconstitution, not sodium chloride solution. Using the wrong diluent can result in incorrect drug concentrations and potential harm to the patient.

c. Discard any remaining medication after 10 days: This option is correct. The label clearly states that the reconstituted medication should be discarded after 10 days. This is important information for safe medication administration.

d. Roll the vial gently in hands to mix the medication: This option is incorrect. The label instructions specify shaking vigorously to wet the powder and then adding the remaining water, followed by vigorous shaking. Rolling the vial gently is not mentioned in the label instructions.

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Naxlex Comprehensive Predictor Exams

Correct Answer is ["0.71"]

Explanation

Correct Answer is C

Explanation

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