A nurse is working in an adult Inpatient unit caring for patient's with inflammatory bowel disease. The nurse knows the following medications are commonly used for treatment of Chron's or Ulcerative Colitis. Select all that apply.
lisdexamfetamine
mesalamine
adalimumab
budesonide
Datorvastatin
Correct Answer : B,C,D
A. lisdexamfetamine: Lisdexamfetamine is a central nervous system stimulant used primarily to treat attention-deficit/hyperactivity disorder (ADHD) and binge-eating disorder. It has no anti-inflammatory or immunomodulatory effects and is not used in the management of Crohn’s disease or ulcerative colitis.
B. mesalamine: Mesalamine is an aminosalicylate that acts locally in the gastrointestinal tract to reduce inflammation. It is commonly used in both Crohn’s disease and ulcerative colitis to induce and maintain remission, particularly for mild to moderate disease activity.
C. adalimumab: Adalimumab is a monoclonal antibody that inhibits tumor necrosis factor-alpha (TNF-α), a key pro-inflammatory cytokine involved in inflammatory bowel disease. It is indicated for moderate to severe Crohn’s disease and ulcerative colitis, particularly in clients who do not respond to conventional therapy.
D. budesonide: Budesonide is a corticosteroid with high topical anti-inflammatory activity in the GI tract and lower systemic absorption than systemic steroids. It is used to treat mild to moderate flares of Crohn’s disease and sometimes ulcerative colitis, reducing inflammation while minimizing systemic side effects.
E. datorvastatin: Datorvastatin is a statin used for hyperlipidemia and cardiovascular risk reduction. It has no role in the management of inflammatory bowel disease and does not affect intestinal inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Diverticulitis: Diverticulitis typically presents in older adults with left lower quadrant abdominal pain, fever, and sometimes changes in bowel habits. While diarrhea can occur, chronic bloody stools and systemic symptoms like weight loss are not characteristic. Extraintestinal manifestations such as joint pain are uncommon in diverticulitis.
B. Colon cancer: Colon cancer may cause changes in bowel habits, occult bleeding, and weight loss, but it is less common in young adults and usually does not present with recurrent diarrhea, fecal urgency, or widespread joint pain. The combination of bloody stools and systemic inflammatory symptoms points to an inflammatory bowel disease rather than malignancy.
C. Ulcerative Colitis: Ulcerative colitis typically presents with bloody diarrhea, fecal urgency, cramping abdominal pain (commonly in the left lower quadrant), and weight loss. Extraintestinal manifestations, including arthritis affecting large joints such as elbows and knees, are common. The client’s age, symptom pattern, and joint involvement strongly support ulcerative colitis.
D. Crohn Disease: Crohn’s disease can cause diarrhea, abdominal pain, weight loss, and extraintestinal symptoms. However, Crohn’s often involves the terminal ileum and presents with patchy, transmural inflammation. Bloody diarrhea is less prominent than in ulcerative colitis, and pain is more often right-sided or diffuse rather than strictly left lower quadrant.
Correct Answer is A
Explanation
A. Slow, irregular respirations: Increasing intracranial pressure can compress or damage the brainstem, which controls basic respiratory function. As the pressure rises, the normal rhythmic drive of the medulla and pons becomes impaired, resulting in slow, irregular, or even intermittent breathing patterns. This is a hallmark sign of brainstem involvement and worsening neurological status.
B. Rapid, shallow respirations: Rapid, shallow breathing is more commonly associated with metabolic acidosis, hypoxia, or pain rather than direct brainstem compromise. While it reflects respiratory distress, it does not specifically indicate increased intracranial pressure.
C. Nasal flaring: Nasal flaring is a sign of increased work of breathing and is typically seen in pediatric patients with respiratory distress. It does not reflect brainstem dysfunction or elevated intracranial pressure.
D. Asymmetric chest excursion: Unequal chest expansion indicates localized lung or musculoskeletal issues, such as pneumothorax, atelectasis, or muscle weakness. It is not a direct indicator of increased intracranial pressure or brainstem involvement.
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