A patient is receiving an IV of esmolol 2.5 grams in 250 mL of D5W (dextrose 5% in water) infusing at 200 micrograms/kilogram/minute. The patient weighs 110 lb. What rate (in mL/hr) should the nurse program into the IV pump to deliver this dose?

This statement is correct because the abdomen has a large surface area and a good blood supply, which allows for a consistent and predictable absorption of insulin. Insulin is a hormone that regulates blood glucose levels and needs to be delivered in precise doses to avoid complications such as hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose).

The abdomen is also easy to access and has less variation in fat thickness, which reduces the risk of injecting into the muscle or the skin instead of the subcutaneous tissue. The subcutaneous tissue is the layer of fat and connective tissue below the skin and above the muscle, where insulin injections are given.

The other statements are not correct because they do not explain why the abdomen is the preferred site for subcutaneous insulin injections or they contain false information.

a.It is the least painful location for this injection. This statement is false because pain is subjective and depends on many factors, such as the type and size of the needle, the technique and speed of injection, the temperature and viscosity of the insulin, and the individual's pain tolerance and sensitivity. The abdomen may not be the least painful location for everyone, and some people may prefer other sites, such as the arms, thighs, or butocks.
b.There are fewer insulin side effects when given in this site. This statement is false because insulin side effects are not related to the site of injection, but to the dose, type, and timing of insulin, as well as the individual's response to insulin and other factors, such as diet, exercise, stress, illness, and medications. Insulin side effects may include hypoglycemia, weight gain, allergic reactions, lipodystrophy (changes in fat tissue), or edema (swelling).
c.It causes less bruising at the site. This statement is false because bruising is caused by bleeding under the skin due to damage to blood vessels during injection. Bruising can occur at any site of injection and depends on many factors, such as the type and size of the needle, the technique and speed of injection, the pressure applied after injection, the individual's clotting ability and blood thinning medications, and the presence of any underlying conditions that affect blood vessels or circulation.

To find the rate in mL/hr, you need to use the formula for infusion rate:

Infusion rate (mL/h) = (Total volume (mL) x Flow factor (gt/mL)) / Time (min) x 60 min/h

Since the total volume is 50 mL, the flow factor is 1 gt/mL, and the time is 15 minutes, plug in these values into the formula:

Infusion rate (mL/h) = (50 mL x 1 gt/mL) / 15 min x 60 min/h

Simplify and solve for the infusion rate:

Infusion rate (mL/h) = 200 mL/h

Therefore, the nurse should set the IV pump to deliver **200 mL/h** to infuse Regian 10 mg over 15 minutes.