A patient is receiving warfarin (Coumadin), which is 98% bound to plasma proteins. The antidepressant paroxetine (Paxil), which is 95% bound to plasma proteins, is added to the patient's daily medication. If the paroxetine displaces warfarin from its protein binding sites, which of the following will most likely to occur?

Diminished effect from warfarin

Diminished effect from paroxetine

Increased effect, and toxicity from paroxetine

Increased effect, and toxicity from warfarin

Answer and Explanation

The Correct Answer is D

A. Diminished effect from warfarin: This is unlikely because displacement of warfarin from protein binding sites would increase its concentration in the bloodstream, potentially leading to increased anticoagulant effects and toxicity.

B. Diminished effect from paroxetine: This is also unlikely because displacement of paroxetine from protein binding sites would increase its concentration in the bloodstream, potentially leading to increased pharmacological effects and toxicity.

C. Increased effect, and toxicity from paroxetine: If paroxetine displaces warfarin from protein binding sites, it can increase the concentration of free warfarin in the bloodstream, leading to increased anticoagulant effects and potential toxicity.

D. Increased effect, and toxicity from warfarin: Correct. If warfarin is displaced from protein binding sites by paroxetine, it can increase the concentration of free warfarin in the bloodstream, leading to increased anticoagulant effects and potential toxicity.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is {"dropdown-group-1":"A"}

Explanation

A. Whole: Complementary and alternative medicine (CAM) emphasizes treating the entire person, considering physical, mental, emotional, and spiritual aspects of health. It aims to restore balance and promote overall well-being.

B. Diseased: CAM focuses on addressing the root cause of illness, not just treating the symptoms of a disease. While disease management can be a part of CAM, it's not the sole focus.

C. Partial: CAM doesn't focus on treating only a part of the person. It aims for a comprehensive approach.

D. Impaired: While CAM can be used to address impairments, it has a broader scope that encompasses promoting overall health and preventing illness, not just treating existing limitations

A. To prevent overuse of prescription medications B. Because herbal therapies are so much safer than manmade drugs C. To increase feelings of wellness and promote holistic treatment D. Because herbal therapies are much more regulated than prescription drugs

Correct Answer is C

Explanation

A. To prevent overuse of prescription medications: While some patients may use herbal therapies as an alternative to avoid overuse of prescription medications, this is not the primary reason for the widespread use of herbal therapies. People often turn to herbal remedies for their perceived natural benefits and to complement conventional treatments, rather than to prevent overuse.

B. Because herbal therapies are so much safer than manmade drugs: This is a common misconception. Herbal therapies are not necessarily safer than prescription drugs. They can have potent effects and interact with medications, potentially causing adverse reactions. The safety of herbal remedies varies widely depending on the specific herb and its use.

C. To increase feelings of wellness and promote holistic treatment: Many patients use herbal therapies as part of a holistic approach to health. They seek to improve overall wellness, balance, and harmony in their body, mind, and spirit. Herbal therapies are often integrated into a lifestyle that values natural and preventive health measures.

D. Because herbal therapies are much more regulated than prescription drugs: This statement is incorrect. Herbal therapies are generally less regulated than prescription drugs. In many countries, herbal supplements are not subject to the same rigorous testing and approval processes as prescription medications, leading to variability in quality and potency.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Complementary and alternative medicine focuses on treating the person using natural products and mind-body therapies.

Correct Answer is {"dropdown-group-1":"A"}

Explanation

Patients often use herbal therapies for which of the following reasons?

Correct Answer is C

Explanation

A nurse is preparing to administer amoxicillin 350 mg PO. Available is amoxicillin 250 mg/5 mL. How many mL should the nurse administer? (Round to the nearest whole number.)

Which of the following statements would most likely NOT be allowed on the label of a dietary supplement?

Unlike heparin, the anticoagulant activity of warfarin can take several to reach its maximum effect.

The patient is to be started on warfarin (Coumadin) therapy. It is important for the nurse to check for the use of which herbs? (Select All that Apply.)

Which of the following clump and adhere to the wall of the injured blood vessel to begin the process of hemostasis?

A nurse is collecting data from a client who is receiving clopidogrel following the placement of a cardiac stent. Which of the following findings should the nurse identify as an adverse effect of this medication?

The patient has been started on warfarin (Coumadin) for deep vein thrombosis. The patient asks when the medication will break up the clots. The nurse's best response would be: