A patient is taking benzodiazepines for anxiety.
Which adverse effect should the nurse warn about?
Hypertension.
Respiratory depression.
Hyperactivity.
Increased alertness.
The Correct Answer is B
Choice A rationale
Benzodiazepines, such as diazepam, are central nervous system depressants. Their primary action is to enhance the effect of the neurotransmitter GABA, which results in sedative, anxiolytic, and muscle-relaxant properties. This mechanism of action often leads to a decrease, not an increase, in blood pressure. Therefore, hypertension is not an anticipated adverse effect.
Choice B rationale
Benzodiazepines enhance the inhibitory effects of GABA throughout the central nervous system, including the brainstem respiratory centers. This can lead to a significant dose-dependent depression of respiratory drive. This effect is particularly dangerous when these medications are combined with other CNS depressants like opioids or alcohol, leading to potentially fatal respiratory arrest.
Choice C rationale
Benzodiazepines are known to cause central nervous system depression, leading to sedation and decreased psychomotor activity. They are prescribed to treat anxiety and insomnia, and their intended effects are calming and sedating. Hyperactivity, which is an increase in activity and restlessness, is the opposite of the expected pharmacological effect and is not a typical adverse reaction.
Choice D rationale
Benzodiazepines are known to decrease alertness and cause drowsiness due to their central nervous system depressant effects. This is a common and expected side effect, especially at higher doses or with initial use. Advising a patient about decreased alertness is essential for safety, as it can impair their ability to perform tasks requiring focus.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
While following the medication schedule strictly is a crucial part of medication administration, it is not the absolute priority. Administering a medication at the wrong time could potentially harm the patient if other checks are not performed first, highlighting that the core safety checks are the foremost priority.
Choice B rationale
Ensuring the patient takes the medication correctly is an important step in the process, but it follows the initial and more critical steps of verifying the medication and dose. If the incorrect drug is prepared or the wrong dose is calculated, the act of the patient taking it correctly becomes irrelevant and potentially dangerous.
Choice C rationale
The nurse's highest priority is to confirm the right medication, dose, route, and patient, as this practice, known as the "five rights," is the cornerstone of patient safety. This step minimizes the risk of administering the wrong drug, the wrong dose, or to the wrong patient, which could lead to severe adverse outcomes.
Choice D rationale
Documentation is a vital part of the medication administration process for legal and continuity of care purposes, but it must be done after the medication has been administered. Documenting before the action is completed can lead to errors and is not considered a safe practice, therefore it cannot be the priority.
Correct Answer is A
Explanation
Choice A rationale
Ranolazine (Ranexa) is an antianginal agent that works by inhibiting the late sodium current in cardiac myocytes. This inhibition leads to a reduction in intracellular calcium overload, improving myocardial relaxation and reducing ventricular wall tension. Unlike many other antianginal drugs, ranolazine does not significantly affect heart rate or blood pressure, making it useful in patients who cannot tolerate the hemodynamic effects of other agents.
Choice B rationale
Ranolazine is not a first-line therapy for angina. It is typically used as a second-line treatment in patients who have not achieved adequate symptom control with beta-blockers, calcium channel blockers, or nitrates. It is often prescribed in combination with other antianginal drugs.
Choice C rationale
Ranolazine is an oral medication available in an extended-release tablet formulation. It is not administered intravenously. The patient takes this medication by mouth, usually twice daily, for the long-term management of chronic angina.
Choice D rationale
Ranexa is metabolized by the liver, specifically via the cytochrome P450 3A (CYP3A) enzyme pathway. Therefore, it is contraindicated or requires significant dose adjustment in patients with moderate to severe hepatic impairment due to the risk of increased plasma concentrations and toxicity.
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