A patient with coronary artery disease is to start low-dose aspirin therapy.
What is the primary reason for this medication?
To relieve chest pain.
To decrease blood pressure.
To prevent clot formation.
To reduce cholesterol levels.
The Correct Answer is C
Choice A rationale
Aspirin is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties, but it is not the primary reason for low-dose therapy in coronary artery disease. Aspirin's analgesic effect is achieved at higher doses. The primary goal of low-dose aspirin in this context is its antiplatelet effect, not pain relief, as it does not effectively address the chest pain associated with myocardial ischemia, which is typically managed with vasodilators like nitroglycerin.
Choice B rationale
Aspirin does not have a direct blood pressure-lowering effect. While it can reduce inflammation and vascular resistance in some cases, it is not prescribed as an antihypertensive medication. Angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), and beta-blockers are the primary classes of medications used to manage high blood pressure in patients with coronary artery disease.
Choice C rationale
Low-dose aspirin inhibits the production of thromboxane A2 by irreversibly acetylating cyclooxygenase (COX-1) in platelets. Thromboxane A2 is a potent vasoconstrictor and platelet aggregator. By inhibiting its production, aspirin prevents platelets from clumping together, which reduces the risk of clot formation in the coronary arteries and helps prevent myocardial infarction and other cardiovascular events.
Choice D rationale
Aspirin does not significantly reduce cholesterol levels. Statin medications, such as atorvastatin or rosuvastatin, are the class of drugs primarily used to lower cholesterol. They work by inhibiting HMG-CoA reductase, an enzyme involved in cholesterol synthesis in the liver. Aspirin's role is specifically to prevent thrombotic events, not to address the underlying lipid-related pathology.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Administering a medication when there is a strong possibility the patient has already received it could lead to an overdose. The automated dispensing machine's record indicates removal of the dose, and the patient's statement, despite her confusion, suggests she might have taken it. The nurse's primary responsibility is patient safety and preventing medication errors, which this action would violate.
Choice B rationale
This is the safest course of action. The medication was removed from the machine, and the patient states she thinks she took it. The night shift nurse's failure to sign the MAR is a documentation error, but the potential for a double dose is a serious safety concern. The nurse should hold the dose and investigate further before administering anything to prevent an iatrogenic event.
Choice C rationale
Notifying the provider for a new order is an unnecessary and premature step. The issue is not that the medication is unavailable or the order is incorrect. The immediate concern is whether the patient has already received the dose. Holding the medication and verifying the administration is the correct first step, and the provider would not be contacted unless there was a clinical reason to do so, such as if the blood glucose became dangerously high.
Choice D rationale
Giving the insulin and then monitoring the patient is dangerous. Administering an additional dose of insulin could cause a severe hypoglycemic event, especially in a confused patient. The blood glucose of 142 mg/dL is not critically high, so there is no immediate need for the insulin, and the risk of a medication error outweighs any perceived benefit of administering the medication immediately.
Correct Answer is A
Explanation
Choice A rationale
When mixing insulin lispro (rapid-acting) with NPH (intermediate-acting), it is a standard and crucial procedure to draw the clear rapid-acting insulin first, followed by the cloudy NPH insulin. This is to prevent the contamination of the rapid-acting vial with the NPH suspension, which could alter the rapid-acting insulin's predictable onset and peak.
Choice B rationale
While unopened insulin vials should be stored in the refrigerator, the patient's current in-use vials can be stored at room temperature for up to 28 days to make injections more comfortable. Injecting cold insulin can cause discomfort and lipohypertrophy at the injection site. However, the refrigerator is where all unopened vials are stored.
Choice C rationale
Shaking the insulin for a full minute is not recommended. Vigorous shaking can cause foaming and bubble formation, which can lead to inaccurate dosing. NPH insulin, a suspension, should be gently rolled between the palms to ensure uniform mixing and proper suspension of the particles, which prevents clumping and allows for accurate dosing.
Choice D rationale
Administering an injection at a 30-degree angle is not standard practice for subcutaneous insulin injections. Insulin is injected into the subcutaneous fat layer. A 90-degree angle is commonly used for most patients, and a 45-degree angle may be used for very thin individuals or for injections into the arms. A 30-degree angle is not correct.
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