A surgical patient with a known genetic predisposition to malignant hyperthermia is undergoing anesthesia.
Which of the following is the most critical immediate action for the perioperative team if signs of malignant hyperthermia, such as muscle rigidity and tachycardia, are observed?
Initiate a cool water bath to reduce body temperature.
Administer oxygen therapy to the patient.
Increase the volume of intravenous fluids being administered.
Administer dantrolene sodium immediately.
The Correct Answer is D
Choice A rationale
While hyperthermia is a sign of this condition, a cool water bath is not the most critical or immediate life-saving intervention. Malignant hyperthermia is a biochemical crisis triggered by volatile anesthetics, causing a massive release of calcium from the sarcoplasmic reticulum. Cooling measures are supportive and should be initiated once the primary pharmacological reversal is underway. The priority is to stop the underlying hypermetabolic process rather than simply treating the symptom of elevated temperature.
Choice B rationale
Administering oxygen is a standard part of the resuscitation protocol for malignant hyperthermia because the patient's metabolic rate increases three to five fold, leading to respiratory and metabolic acidosis. However, providing oxygen alone does not stop the calcium-induced muscle rigidity or the hypermetabolic cascade. While vital for maintaining cellular oxygenation during the crisis, it is considered a secondary supportive measure that must follow the administration of the specific antagonist required to stabilize muscle cell membranes.
Choice C rationale
Increasing intravenous fluids is necessary to maintain renal perfusion and prevent acute kidney injury caused by rhabdomyolysis and the resulting myoglobinuria. However, fluid resuscitation is not the most critical immediate action when compared to the need for a specific muscle relaxant. Fluids help manage the complications of the crisis, such as hyperkalemia and pigment-induced nephropathy, but they do not address the lethal intracellular calcium shift that characterizes the primary pathophysiology of the anesthetic reaction.
Choice D rationale
Dantrolene sodium is the only specific treatment for malignant hyperthermia. It works by binding to ryanodine receptors, which inhibits the release of calcium from the sarcoplasmic reticulum into the cytosol. This action effectively halts the uncontrolled muscle contractions and hypermetabolism. Immediate administration is vital to prevent multi-organ failure and death. The perioperative team must also stop the triggering anesthetic agents and hyperventilate the patient with 100 percent oxygen as they prepare the dantrolene for rapid infusion. .
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Scheduling a CT scan is a diagnostic step used to identify adrenal adenomas or hyperplasia, which are common causes of primary hyperaldosteronism. However, in an acute presentation with a blood pressure of 220/135 mmHg, diagnostic imaging is not the immediate priority. The patient is experiencing a hypertensive crisis, which requires urgent physiological stabilization. While imaging is necessary for long-term treatment planning, the nurse must first address the life-threatening hemodynamic instability and electrolyte imbalances to prevent end-organ damage.
Choice B rationale
A low-sodium diet is a long-term management strategy for hyperaldosteronism to help control fluid retention and hypertension. However, in the presence of a hypertensive emergency, dietary modifications are insufficient and too slow to be effective. The patient requires immediate pharmacological intervention to lower blood pressure and prevent a cerebrovascular accident or myocardial infarction. Initial nursing actions must focus on acute interventions that produce rapid physiological changes rather than lifestyle or dietary adjustments that take days to manifest.
Choice C rationale
Monitoring for signs of fluid overload is the priority because aldosterone causes the kidneys to retain sodium and water while excreting potassium. Excess aldosterone leads to an expanded intravascular volume, contributing to the severe hypertension of 220/135 mmHg. The nurse must assess for peripheral edema, jugular venous distention, and pulmonary crackles. Managing volume status is critical to preventing heart failure and further escalation of the hypertensive crisis, making it the most vital assessment for a patient in this state.
Choice D rationale
Administering potassium supplements is necessary to correct the hypokalemia of 3.1 mEq/L, as the normal range is 3.5 to 5.0 mEq/L. However, potassium must be replaced with extreme caution in the setting of severe hypertension and potential renal impairment. While correcting the heart's electrical stability is important, the immediate threat to the patient's life is the extremely high blood pressure. Monitoring the systemic effects of the fluid and electrolyte imbalance takes precedence to guide safe administration of intravenous medications. .
Correct Answer is ["C","D","E","F"]
Explanation
Choice A rationale
Intense physical activity in cold weather generally increases metabolic heat production and improves core temperature maintenance, which can actually be protective against frostbite as long as the person remains dry. While exhaustion can eventually lead to a drop in body temperature, the activity itself is not a direct risk factor compared to environmental exposure or poor circulation. Therefore, active movement is usually encouraged to maintain peripheral perfusion during brief periods of cold exposure to prevent freezing.
Choice B rationale
A high caloric intake before entering a cold environment provides the body with necessary fuel for thermogenesis and shivering, which helps maintain the core body temperature. Malnutrition or an empty stomach would be a risk factor because the body lacks the energy stores needed to generate heat effectively. Therefore, eating a hearty meal is a protective strategy rather than a risk factor for the development of cold-induced tissue injuries like frostbite or systemic hypothermia.
Choice C rationale
Inadequate clothing is a primary risk factor because it allows for rapid heat loss through conduction, convection, and radiation. Without proper insulation, the skin is directly exposed to freezing temperatures, leading to the formation of ice crystals in the extracellular fluid and subsequent cellular dehydration. Protecting the extremities with moisture-wicking layers and wind-resistant outer shells is essential to maintain a microclimate that prevents the skin temperature from dropping below the freezing point.
Choice D rationale
Conditions such as peripheral vascular disease, diabetes mellitus, or Raynaud's phenomenon significantly increase the risk of frostbite by impairing the body's ability to deliver warm blood to the extremities. When blood flow is compromised, the tissues cannot effectively counteract the cooling effects of the environment. Chronic vascular insufficiency reduces the thermal reserve of the skin, making the fingers, toes, and nose much more susceptible to freezing even during relatively short periods of cold exposure.
Choice E rationale
The duration of exposure to sub-zero temperatures is a critical determinant in the pathophysiology of frostbite. Prolonged exposure allows the cold to penetrate deeper into the tissues, causing progressive vasoconstriction and eventual vascular stasis. As the exposure time increases, the risk of irreversible tissue damage and necrosis rises because the compensatory mechanisms of the body are overwhelmed. Freezing of the skin and underlying structures occurs when the tissue temperature falls below 0 degrees Celsius.
Choice F rationale
Consuming alcohol causes peripheral vasodilation, which creates a false sense of warmth while actually accelerating the loss of core body heat to the environment. Furthermore, alcohol impairs cognitive judgment and physical coordination, potentially leading a person to remain in a cold environment longer than is safe or to lose protective clothing. This combination of physiological heat loss and behavioral impairment significantly predisposes an individual to severe cold injuries and systemic hypothermia in freezing conditions.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.
