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In girls, what is the first sign of puberty?

A.

Growth of pubic hair

B.

Growth spurt

C.

Breast bud development

D.

Menarche

Answer and Explanation

The Correct Answer is C

Rationale:

A. Growth of pubic hair: Pubic hair growth, or pubarche, typically occurs after the initial signs of puberty and is a secondary sexual characteristic, not the first sign.

B. Growth spurt: The rapid increase in height follows the onset of puberty but usually comes after breast development has started.

C. Breast bud development: Thelarche, or breast bud development, is the earliest visible sign of puberty in girls, marking the start of hormonal changes and sexual maturation.

D. Menarche: Menarche, the onset of menstruation, occurs later in puberty after several other physical changes, including breast development and growth spurt.


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Related Questions

Correct Answer is ["2400"]

Explanation

Calculation:

Dose per administration = 400 mg.

  • Calculate the number of doses in one 24-hour period.

Number of doses = Total hours / Frequency of administration

= 24 hours / 4 hours/dose

= 6 doses.

  • Calculate the total milligrams (mg) the child will receive in a 24-hour period.

Total mg = Dose per administration (mg) x Number of doses

= 400 mg x 6 doses

= 2400 mg.

Correct Answer is {"dropdown-group-1":"B","dropdown-group-2":"A"}

Explanation

Rationale for Correct Choices:

• Cracked lips and strawberry tongue are hallmark mucocutaneous changes in Kawasaki disease, reflecting widespread inflammation of mucous membranes in the acute phase. These are often accompanied by conjunctival injection and rash.

• Aspirin and IV gamma globulin are the mainstay treatments for Kawasaki disease, reducing inflammation and significantly lowering the risk of coronary artery aneurysms when given early in the illness.

Rationale for Incorrect Choices:

• Petechiae and purpura rash are more commonly seen in platelet or clotting disorders such as idiopathic thrombocytopenic purpura or meningococcemia. Kawasaki disease typically presents with diffuse erythematous rash, not pinpoint hemorrhages.

• Polyarthritis may occur in the later stages of Kawasaki disease, but chorea is a neurological manifestation linked to rheumatic fever. This combination does not fit the acute presentation of Kawasaki disease.

• Corticosteroids and antibiotics are not first-line treatments for Kawasaki disease. Antibiotics are ineffective as the cause is not bacterial, and corticosteroids are generally reserved for IVIG-resistant cases.

• ACE inhibitors and NSAIDs are not standard therapy for Kawasaki disease. ACE inhibitors are used in hypertension or heart failure, and NSAIDs are not as effective as high-dose aspirin in reducing the acute inflammatory response in this condition.

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