In which situation would benzodiazepines be prescribed appropriately?
Long-term treatment of posttraumatic stress disorder, convulsive disorder, and alcohol withdrawal.
Short-term treatment of generalized anxiety disorder, alcohol withdrawal, and preoperative sedation.
Short-term treatment of obsessive-compulsive disorder, skeletal muscle spasms, and essential hypertension.
Long-term treatment of panic disorder, alcohol dependence, and bipolar affective disorder: manic episode.
The Correct Answer is B
Benzodiazepines are central nervous system depressants that enhance the effect of gamma-aminobutyric acid (GABA), producing sedative, anxiolytic, anticonvulsant, and muscle relaxant effects. They are indicated for short-term management of anxiety, alcohol withdrawal, and procedural sedation. Long-term use is discouraged due to risks of dependence, tolerance, and cognitive impairment. Common side effects include drowsiness, confusion, and respiratory depression. Contraindications include sleep apnea, substance use disorders, and concurrent use with opioids or alcohol due to synergistic CNS depression.
Rationale for correct answers
2. Benzodiazepines are appropriate for short-term treatment of generalized anxiety disorder, alcohol withdrawal, and preoperative sedation due to their rapid onset and calming effects. These uses align with their pharmacologic profile and safety guidelines for limited duration.
Rationale for incorrect answers
1. Long-term use for PTSD and convulsive disorders is discouraged due to risk of dependence and tolerance. While benzodiazepines may be used acutely in alcohol withdrawal, chronic use is not recommended.
3. Benzodiazepines are not first-line for obsessive-compulsive disorder or essential hypertension. They may relieve muscle spasms but are not indicated for long-term management of these conditions.
4. Long-term treatment of panic disorder and bipolar mania with benzodiazepines is not standard due to risk of addiction. Alcohol dependence requires structured withdrawal protocols, not maintenance benzodiazepine therapy.
Take Home Points
- Benzodiazepines are best suited for short-term use in anxiety, alcohol withdrawal, and procedural sedation.
- Long-term use increases risk of dependence, tolerance, and cognitive decline.
- They are contraindicated in patients with substance use disorders or respiratory compromise.
- SSRIs and other non-addictive agents are preferred for chronic anxiety and mood disorders.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Risk for suicideis the most urgent concern when a client expresses suicidal ideation. Generalized anxiety disorder may elevate suicide risk, especially when compounded by hopelessness and impaired coping. According to DSM-5, suicidal thoughts in the context of anxiety signal acute distress and require immediate safety interventions. The priority in nursing care is always physiological safety, which aligns with Maslow’s hierarchy of needs—preserving life precedes addressing emotional or psychological concerns.
Rationale for correct answers
4. Risk for suicideis the priority diagnosis because the client has verbalized suicidal ideation. This poses an immediate threat to life and demands urgent intervention, including safety planning and continuous monitoring.
Rationale for incorrect answers
1.Hopelessnessis present but secondary to the suicide risk. While the statement reflects despair, it does not override the need to address the client’s safety first.
2.Ineffective copingmay contribute to suicidal ideation, but it is not the most critical concern. Coping strategies can be addressed after ensuring the client is safe.
3.Anxietyis evident, but it is not the priority when suicidal thoughts are expressed. The rating of 9/10 supports severity, but the suicide risk takes precedence.
Take Home Points
- Suicide risk always takes priority in nursing diagnoses when ideation is present.
- Generalized anxiety disorder can escalate to suicidal thoughts, especially when compounded by hopelessness.
- Maslow’s hierarchy places physiological safety above emotional needs.
- Nursing interventions must focus first on safety, then address underlying emotional and cognitive concerns.
Correct Answer is B
Explanation
Concurrent use of serotonergic agentslike clonazepam, buspirone, and citalopramrequires careful monitoring due to additive central nervous system and serotonergic effects. Clonazepam is a benzodiazepine with sedative and anxiolytic properties. Buspirone is a non-benzodiazepine anxiolytic that modulates serotonin and dopamine receptors. Citalopram is a selective serotonin reuptake inhibitor (SSRI) used for depression and anxiety. When combined, these drugs may increase the risk of serotonin syndrome, CNS depression, and altered mental status. Symptoms may include tremor, diaphoresis, tachycardia, and confusion. Monitoring is essential, especially during initiation or dosage changes.
Rationale for correct answers
2.The combination of citalopram and buspirone increases serotonergic activity, while clonazepam adds CNS depressant effects. This triad can lead to serotonin syndromeand autonomic instability, making it critical to monitor for tremor, diaphoresis, tachycardia, and mental status changes.
Rationale for incorrect answers
1.While worsening depression and suicidal ideation are concerns with SSRIs like citalopram, this is not the most immediate risk when combined with buspirone and clonazepam. The primary concern is serotonin syndromeand CNS effects.
3.Hyperpyrexia, dystonia, and rigidity are more characteristic of neuroleptic malignant syndrome, typically associated with antipsychotics, not the medications listed.
4.Facial spasms and bizarre movements suggest extrapyramidal symptomsor tardive dyskinesia, which are not common with SSRIs, buspirone, or benzodiazepines.
Take Home Points
- Combining SSRIs, buspirone, and benzodiazepines increases risk of serotonin syndrome and CNS depression.
- Serotonin syndrome presents with tremor, tachycardia, diaphoresis, and altered mental status.
- Neuroleptic malignant syndrome and extrapyramidal symptoms are not typical risks with these agents.
- Close monitoring is essential during initiation or dose changes of serotonergic and CNS depressant drugs.
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