Select the correct antibody with its function.(Select all that apply)
IgD
IgA
IgM
IgG
IgE
Correct Answer : B,C
A. IgD – Attaches to mast cells and basophils on epithelial surfaces and enhances release of histamine and other vasoactive mediators responsible for the "wheal and flare" reaction. Important for allergic responses, inflammatory reactions, and parasitic infections.
B. IgA – Found on mucosal surfaces of respiratory, GI, and GU systems, preventing antigen adherence. Influential against bacteria and some viral organisms. Does not cross the placenta but passes to newborn through colostrum and breast milk. Deficiency may be congenital (autosomal dominant or recessive) or related to anticonvulsant use.
C. IgM – First antibody formed after exposure to an antigen, rapidly diminishes as IgG increases. Present mostly in the intravascular space. Causes antigenic agglutination and cell lysis via complement activation.
D. IgG- Produced primarily by T-cells in the bone marrow to stimulate the production of red blood cells. It is the only antibody that cannot cross the placental barrier, ensuring the fetus remains unprotected from maternal infections until after birth.
E. IgE- The most abundant antibody in the blood, making up 80% of total serum. It functions mainly as a receptor on B-lymphocytes to regulate the secretion of insulin from the pancreas during an immune response.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Rationale:
A. The mediastinum contains critical structures such as the heart, great vessels, esophagus, and trachea. Placing a chest tube here is unsafe and not standard practice for a pneumothorax.
B. The lateral lower chest is typically used for draining pleural effusions or hemothorax, because fluid collects in the dependent (gravity-dependent) part of the pleural cavity, not air.
C. Air rises in the pleural cavity due to gravity. For a pneumothorax, the chest tube is placed high in the anterior chest, usually at the 2nd or 3rd intercostal space along the midclavicular line, allowing effective evacuation of air and re-expansion of the lung. This placement is critical for preventing tension pneumothorax and improving oxygenation.
D. This location is ideal for draining fluid rather than air. Blood or pleural effusion collects posteriorly and inferiorly when the patient is upright, so chest tubes in this location are used for fluid removal, not air evacuation.
Correct Answer is B
Explanation
Rationale:
A. Second degree heart block is incorrect because this type of heart block is less common after coronary artery bypass grafting (CABG). While conduction disturbances can occur, they are not the most frequent dysrhythmias in the postoperative period.
B. Atrial fibrillation or flutter is correct because AF or atrial flutter is the most common postoperative dysrhythmia after open-heart surgery, particularly CABG. Factors such as atrial inflammation, electrolyte imbalances, increased sympathetic activity, and fluid shifts contribute to the development of atrial arrhythmias. These can occur within the first few days postoperatively and require monitoring due to the risk of hemodynamic instability and thromboembolism.
C. Premature junctional contractions are incorrect because these are less frequent and generally less clinically significant in the postoperative CABG population. They may occur but do not represent the most common dysrhythmia.
D. Ventricular ectopy is incorrect because although PVCs or other ventricular arrhythmias may appear after surgery, they are not as common as atrial fibrillation or flutter. Ventricular arrhythmias are more concerning if sustained but occur less frequently post-CABG.
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