The directions for reconstitution of levofloxacin for injection are on the drug label. Directions read: "For IM use, add 5.7mt sterile water for injection. Resulting solution contains 250 mg levofloxacin per 1.5 ml. The vial contains levofloxacin equivalent to 1 gram. Usual adult dosage of levofloxacin is 250 mg- 500 mg IM every 4 to 6 hours." What is the final concentration of the prepared levofloxacin for IM administration?
250 mg/1.5 ml.
50mg/1.5 mL
500 mg/1.5 ml.
125 mg/5.7 mL
The Correct Answer is A
A.250 mg/1.5 mL: The label explicitly states the resulting solution contains 250 mg of levofloxacin per 1.5 mL after reconstitution.
B.50 mg/1.5 mL: This undervalues the stated concentration; the label says 250 mg per 1.5 mL, not 50 mg.
C.500 mg/1.5 mL: This overstates the concentration; 500 mg per 1.5 mL is double what the label specifies.
D.125 mg/5.7 mL: This does not match the stated final concentration units. The label provides concentration per 1.5 mL, not per 5.7 mL, and 125 mg/5.7 mL is inconsistent with the given information.
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Related Questions
Correct Answer is A
Explanation
A. Vastus lateralis:The Vastus Lateralis muscle (located on the anterolateral aspect of the thigh) is the preferred and safest site for IM injections in infants and toddlers (up to 3 years old) because it is large, well-developed, and lacks major nerves and blood vessels close to the injection site.
B. Deltoid:The deltoid muscle in the upper arm is not sufficiently developed in a 4-month-old infant. It is only recommended for use in children aged 18 months or older.
C. Dorsal gluteal:This site (upper-outer quadrant of the buttock) is contraindicated in children under 3 years old due to the risk of injury to the underdeveloped sciatic nerve. It is also generally discouraged in all clients due to the risk of nerve damage.
D. Ventrogluteal:While the ventrogluteal site (side of the hip) is the preferred site for older children and adults, it requires a well-developed muscle mass and reliable anatomical landmarks that are often less identifiable and less safe in an infant. The Vastus Lateralis is preferred for this age group.
Correct Answer is D
Explanation
Ordered dose: 120 mg IM.
Available concentration: 50 mg per mL.
Volume needed = 120 ÷ 50 = 2.4 mL per dose.
Correct answer: 2.4 mL/dose.
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