The nurse receives an order to draw a trough level on a patient prescribed Gentamicin via intravenous (IV) infusion.
When is the best time for the nurse to draw the trough level?
30 minutes after infusion is complete.
Before the next dose of Gentamicin.
30 minutes before stopping the infusion.
1 hour after infusion is complete.
The Correct Answer is B
This question focuses on pharmacokinetics and therapeutic drug monitoring. It requires identifying the timing for trough level blood draws, which are essential to ensure the drug concentration remains within the therapeutic range without reaching toxic levels, particularly with narrow-therapeutic-index drugs like gentamicin.
Choice A rationale
Drawing blood 30 minutes after the infusion is complete would measure the peak concentration of the medication. This does not provide information about the lowest drug levels occurring at the end of the dosing interval, which is necessary for trough assessment.
Choice B rationale
The trough level represents the lowest concentration of a drug in the patient's serum, which occurs immediately before the administration of the next dose. Drawing the blood at this time is required to ensure the medication stays within the safe therapeutic range.
Choice C rationale
Drawing blood 30 minutes before stopping the infusion would occur while the medication is still being actively administered. This would result in an inaccurate, elevated serum concentration reading that does not reflect the patient's true trough level for the drug.
Choice D rationale
Drawing the level 1 hour after the infusion is complete would measure a concentration that is still decreasing toward the trough level. This does not provide the required data at the actual minimum concentration point reached before the next scheduled dose.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
This question tests the application of safety protocols to prevent medication errors. It requires identifying evidence-based strategies that minimize distractions and ensure accuracy, such as the "no-interruption zone" and double-checking high-alert medications, which are fundamental to providing safe patient care in clinical environments.
Choice A rationale
Leaving medications at the bedside violates the safety protocol of witnessing the patient ingest the medication. It introduces significant risk for theft, accidental ingestion by others, or failure to ensure the patient actually took the prescribed dose.
Choice B rationale
Preparing medications for multiple clients simultaneously is a high-risk practice that increases the likelihood of mix-ups and medication errors. Safety guidelines require preparing one patient's medications at a time to maintain focus and ensure accuracy for every dose.
Choice C rationale
Interruptions and distractions are primary causes of medication administration errors. Dedicating focused attention to preparation and utilizing a second nurse to double-check high-alert medications are essential safety steps that significantly reduce the potential for adverse drug-related clinical events.
Choice D rationale
While delegation is a nursing skill, the preparation and administration of medication, especially high-alert drugs, should be done with strict adherence to institutional policy. Improper delegation can bypass safety checks, transferring accountability without ensuring the necessary protocols are consistently followed.
Correct Answer is D
Explanation
This question addresses the monitoring requirements for beta-adrenergic antagonists used in ophthalmic preparations. It requires recognizing that even topical medications can cause systemic absorption, leading to cardiovascular effects like bradycardia, which necessitates assessment of the patient's pulse before drug administration.
Choice A rationale
While peripheral pulses assess circulation, they are not the primary systemic cardiovascular parameter affected by beta-blockers. Monitoring the heart rate is more direct and sensitive for detecting the specific systemic adverse effects of this class of ophthalmic medication.
Choice B rationale
Assessing orientation is part of a neurological assessment, not a specific priority for a patient receiving betaxolol eye drops. The nurse focuses on systemic effects relevant to the drug’s pharmacological category, which is cardiovascular rather than neurological in this context.
Choice C rationale
Although beta-blockers can mask the symptoms of hypoglycemia in diabetic patients, monitoring blood sugar is not the standard priority intervention before administering ophthalmic betaxolol. The most immediate systemic concern is potential bradycardia resulting from the drug's beta-1 blocking effects.
Choice D rationale
Betaxolol is a cardioselective beta-1 blocker. Even when administered topically to the eye, it can be systemically absorbed and cause bradycardia. Therefore, the nurse must assess the apical pulse rate before each dose to ensure the heart rate is within safe parameters.
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