What information should be included when educating a client on repaglinide?
Hypoglycemia is a common side effect.
Bruising may occur when taking this medication.
Take this medication at night before bed.
Stop taking if you experience hyperglycemia.
The Correct Answer is A
A. Hypoglycemia is a common side effect: Repaglinide is a meglitinide that stimulates rapid, short-acting insulin release from pancreatic beta cells, increasing the risk of hypoglycemia, especially if meals are skipped or delayed. Client education should emphasize recognizing early signs, carrying a source of glucose, and timing doses with meals to prevent severe hypoglycemia.
B. Bruising may occur when taking this medication: Bruising is not a typical side effect of repaglinide. Unlike anticoagulants or antiplatelet agents, repaglinide does not affect platelet function or clotting pathways, so clients do not need to monitor for unusual bruising as part of routine education.
C. Take this medication at night before bed: Repaglinide should be taken with meals, usually 0–30 minutes before eating, to match insulin secretion with postprandial glucose. Taking it at night without food increases the risk of hypoglycemia, particularly during prolonged fasting or sleep.
D. Stop taking if you experience hyperglycemia: Experiencing high blood glucose does not warrant abrupt discontinuation of repaglinide. Instead, the client should notify the healthcare provider for dose adjustment or evaluation of adherence, diet, or additional therapy while continuing the medication safely.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Thromboembolism: Estradiol, as an estrogen therapy, increases the risk of thromboembolic events by promoting hepatic synthesis of clotting factors and altering the balance of procoagulant and anticoagulant proteins. This can lead to deep vein thrombosis, pulmonary embolism, or stroke, particularly in clients with additional risk factors.
B. Hyperglycemia: Estradiol does not typically cause elevated blood glucose. Its primary metabolic effects involve reproductive and cardiovascular systems, not glucose regulation, so hyperglycemia is not a common adverse effect.
C. Blurry vision: While ocular changes may occur with hormonal fluctuations, blurry vision is not a common or significant adverse effect of estradiol therapy. Severe visual changes would warrant evaluation for other causes.
D. Increased urination: Estradiol does not usually affect urine output. Increased urination is not pharmacologically linked to estrogen therapy and would require assessment for alternative etiologies such as diabetes or diuretic use.
Correct Answer is C
Explanation
A. Levothyroxine 125 mcg once daily: Levothyroxine does not have significant interactions with fentanyl. Co-administration does not increase the risk of respiratory depression or sedation and is generally safe in pain management contexts.
B. Ibuprofen 400 mg PO every 6 hours PRN: NSAIDs like ibuprofen can be safely used alongside fentanyl for additional analgesia. There is no significant pharmacologic interaction that would increase the risk of severe adverse effects such as respiratory depression.
C. Lorazepam 1 mg PO every 8 hours PRN: Both fentanyl and lorazepam are central nervous system (CNS) depressants. Concurrent use can lead to additive effects, significantly increasing the risk of respiratory depression, profound sedation, hypotension, and even death, making this combination particularly concerning.
D. Penicillin 500 mg IV every 8 hours: Penicillin does not interact with fentanyl in a way that would enhance CNS depression or cause serious adverse effects. Co-administration is generally considered safe.
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