What is a significant genetic risk factor for febrile seizures in children?
Having a sibling with asthma.
Having parents with migraine history.
Having a sibling with febrile seizures.
Having a sibling with epilepsy.
The Correct Answer is C
The scenario requires understanding the genetic predisposition and pathophysiology of childhood febrile seizures. Knowledge of inheritance patterns and familial risk factors is essential to distinguish between respiratory conditions, neurological disorders, and the specific recurrence risks associated with simple or complex seizures.
Choice A rationale
. Asthma is a chronic inflammatory airway disease driven by hypersensitivity and environmental triggers. There is no established genetic link between atopy or respiratory hyperreactivity and the neurological threshold required to trigger a seizure during a high fever.
Choice B rationale
. Migraines involve neurovascular changes and cortical spreading depression. While some genetic overlap exists between adult epilepsy and migraine syndromes, parental migraine history is not recognized as a primary significant genetic risk factor for the development of childhood febrile seizures.
Choice C rationale
. Genetics play a critical role in febrile seizures, with a positive family history significantly increasing risk. Having a sibling with the condition suggests a shared genetic vulnerability involving sodium channel mutations that lower the seizure threshold during hyperpyrexia.
Choice D rationale
. Epilepsy involves recurrent unprovoked seizures, whereas febrile seizures are provoked by fever. While a family history of epilepsy slightly increases the risk of later afebrile seizures, it is not the primary genetic indicator for initial childhood febrile seizures.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Understanding acyanotic congenital heart defects involves recognizing conditions where oxygenated blood recirculates through the lungs. The nurse must apply knowledge of how abnormal openings or narrowings create turbulent blood flow, which is detected through specific physical assessment findings like murmurs.
Choice A rationale
Acyanotic defects, such as VSD or ASD, involve left-to-right shunting that creates audible turbulence. This turbulence is manifested as a heart murmur, which is often the first clinical sign found during a routine physical examination of the child.
Choice B rationale
Cyanosis is the hallmark of cyanotic heart defects where deoxygenated blood enters the systemic circulation. In acyanotic defects, systemic oxygen saturation remains within the normal range of 95.
Choice C rationale
Severe hypoxia is characteristic of right-to-left shunts where pulmonary blood flow is obstructed or bypassed. Patients with acyanotic defects usually maintain adequate systemic oxygen levels and do not exhibit the severe respiratory distress associated with profound hypoxia.
Choice D rationale
Peripheral edema is a sign of congestive heart failure, which can eventually occur as a complication of acyanotic defects. However, it is not an immediate or common initial sign of the congenital defect itself in many pediatric cases.
Correct Answer is C
Explanation
Assessment for meningeal irritation requires understanding the neurological manifestations of inflammation in the central nervous system. Knowledge of spinal cord anatomy and the mechanical effects of dural stretching is necessary to correctly identify and perform the Brudzinski and Kernig clinical signs.
Choice A rationale
Pain and resistance to leg extension when the hip is flexed describes a positive Kernig sign, not Brudzinski. This occurs because stretching the inflamed meninges and spinal roots causes protective muscle guarding and significant discomfort in patients with meningitis.
Choice B rationale
General neck pain during flexion is a symptom of nuchal rigidity but does not specifically define the Brudzinski sign. Nuchal rigidity is a broad clinical finding where the neck muscles are too stiff to allow for chin-to-chest movement without pain.
Choice C rationale
A positive Brudzinski sign occurs when passive flexion of the neck triggers involuntary flexion of the hips and knees. This is a reflexive postural response to the tension placed on the inflamed meninges and spinal cord during the neck maneuver.
Choice D rationale
Neck flexion causing shoulder rotation is not a recognized clinical indicator of meningeal irritation. Neurological assessments focus on the tension of the spinal axis; therefore, hip and knee flexion are the specific indicators looked for in this diagnostic test..
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