Which of the following drugs that are used to treat inflammation are both anti- inflammatory and immunosuppressant?
Aspirin
Cortisone
Ibuprofen
Celecoxib
Meloxicam
The Correct Answer is B
A. Aspirin: Aspirin is an NSAID with anti-inflammatory effects but it is not classically immunosuppressive.
B. Cortisone: Cortisone (a glucocorticoid) has both anti-inflammatory and immunosuppressive actions (reduces cytokine production, lymphocyte activity, etc.).
C. Ibuprofen: Ibuprofen is an NSAID (anti-inflammatory/analgesic) but not an immunosuppressant.
D. Celecoxib: Celecoxib (a COX-2 inhibitor) is anti-inflammatory but not immunosuppressive.
E. Meloxicam: Meloxicam is an NSAID with anti-inflammatory effects but does not produce the broad immunosuppression seen with glucocorticoids.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. acute: A short-term illness with rapid onset, high fever and severe pain fits the definition of acute - sudden onset, relatively brief duration.
B. latent: Latent means hidden or in an incubation/dormant phase (no/minimal symptoms), not a rapidly symptomatic illness.
C. chronic: Chronic refers to long-lasting or recurrent conditions, not short-term, rapidly severe illness.
D. secondary: Secondary describes an illness that results from or follows another condition - it’s a causal qualifier, not a time-course descriptor.
E. manifestation: A manifestation is a sign or symptom of disease, not a type of illness itself.
Correct Answer is A
Explanation
A. Formation of granulomas: Granuloma formation is a feature of chronic inflammation (organized collection of macrophages), not a routine step in the acute inflammatory response. (Not a step.)
B. Release of histamine: Histamine release (from mast cells, basophils) is an early mediator in acute inflammation causing vasodilation and increased permeability.
C. Arteriole dilation: Arteriolar (and precapillary) dilation is a vascular change in acute inflammation that increases blood flow (redness, heat).
D. Increase blood flow: Increased blood flow (hyperemia) is a hallmark vascular feature of acute inflammation producing warmth and redness.
E. Phagocytosis: Phagocytosis by neutrophils and macrophages is a key cellular event in acute inflammation to remove microbes/debris.
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