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Chorionic Villus Sampling (CVS

  • CVS is a prenatal diagnostic test that involves obtaining a small sample of placental tissue (chorionic villi) for chromosomal analysis

    • CVS can detect chromosomal abnormalities such as Down syndrome, trisomy 13, trisomy 18, Turner syndrome, Klinefelter syndrome, .
    • CVS can also detect some genetic disorders such as cystic fibrosis, Tay-Sachs disease, sickle cell disease, .
    • CVS cannot detect neural tube defects such as spina bifida or anencephaly
    • CVS is usually performed between 10 and 13 weeks of gestation
    • CVS can be done by two methods: transcervical or transabdominal
    • Transcervical CVS involves inserting a thin catheter through the cervix and suctioning a small amount of chorionic villi under ultrasound guidance
    • Transabdominal CVS involves inserting a thin needle through the abdomen and uterus and aspirating a small amount of chorionic villi under ultrasound guidance
    • CVS has a risk of miscarriage of about 0.5% to 1%

    • CVS has a risk of infection, bleeding, cramping, leaking of amniotic fluid, Rh sensitization, limb defects.

    • CVS results are usually available within 10 to 14 days.

Questions on Chorionic Villus Sampling (CVS

Correct Answer is C

Explanation

It describes the transcervical procedure, but with a needle instead of a catheter.

Correct Answer is A

Explanation

You may not experience neural tube defects after the procedure. Neural tube defects are birth defects that affect the brain and spinal cord of the baby. CVS cannot detect these conditions, but amniocentesis can. Therefore, women who undergo CVS also need a follow-up blood test between 16 to 18 weeks of their pregnancy to screen for neural tube defects.

Correct Answer is A

Explanation

CVS cannot detect neural tube defects such as anencephaly. Anencephaly is a severe condition where the baby is born without parts of the brain and skull. As mentioned above, CVS does not provide information on neural tube defects, so women who undergo CVS also need a follow-up blood test between 16 to 18 weeks of their pregnancy to screen for these conditions.

The procedure has a risk of bleeding of about 1% to 2%. This is caused by the disruption of blood vessels in the placenta during the sampling.

Results are not usually available within 30 days. This is much longer than the usual time frame for both the rapid and the final result.
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