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Indications for use
Indications for use ( 5 Questions)
A nurse is reviewing the culture and sensitivity report of a client with a urinary tract infection. The report shows that the causative microorganism is Escherichia coli and it is sensitive to ciprofloxacin, nitrofurantoin, and trimethoprim-sulfamethoxazole.
Which of these antimicrobial agents is considered a narrow-spectrum drug?
Choice A is wrong because Ciprofloxacin is a broad-spectrum drug that can affect a wide range of bacteria, both gram-positive and gram-negative.
Nitrofurantoin is considered a narrow-spectrum drug because it is effective against only a limited range of bacteria, mainly gram-negative bacteria that cause urinary tract infections.
Choice C is wrong because Trimethoprim-sulfamethoxazole is also a broad-spectrum drug that can inhibit the growth of many types of bacteria, including some gram-positive and gram-negative bacteria.
Choice D is wrong because None of them is incorrect because nitrofurantoin is a narrow-spectrum drug as explained above.
Nitrofurantoin is considered a narrow-spectrum drug because it is effective against only a limited range of bacteria, mainly gram-negative bacteria that cause urinary tract infections.
Some additional explanations are:
Choice A is wrong because Ciprofloxacin is a broad-spectrum drug that can affect a wide range of bacteria, both gram-positive and gram-negative.
Choice C is wrong because Trimethoprim-sulfamethoxazole is also a broad-spectrum drug that can inhibit the growth of many types of bacteria, including some gram-positive and gram-negative bacteria.
Choice D is wrong because None of them is incorrect because nitrofurantoin is a narrow-spectrum drug as explained above.
Normal ranges for urinary tract infection microorganisms are:
• Escherichia coli: less than 10^5 CFU/mL
• Other bacteria: less than 10^4 CFU/mL