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More questions on this topic ( 31 Questions)
A nurse is preparing to administer ceftriaxone (Rocephin) to a client who has pneumonia caused by Streptococcus pneumoniae.
The nurse should recognize that ceftriaxone belongs to which generation of cephalosporins?
Choice A is wrong because first-generation cephalosporins have less activity against gram-negative bacteria and are more susceptible to beta-lactamases.
Choice B is wrong because second-generation cephalosporins have less activity against Streptococcus pneumoniae than third-generation cephalosporins, and are also less resistant to beta-lactamases.
Ceftriaxone belongs to the third-generation of cephalosporins. Third-generation cephalosporins have greater activity than the second-generation cephalosporins against certain gram-negative bacteria, such as Streptococcus pneumoniae. They are also more resistant to beta-lactamases, enzymes that can inactivate some cephalosporins.
Choice D is wrong because fourth-generation cephalosporins have a broader spectrum of activity against gram-negative bacteria, including some that are resistant to third-generation cephalosporins, but they are not more effective against Streptococcus pneumoniae.
Ceftriaxone belongs to the third-generation of cephalosporins. Third-generation cephalosporins have greater activity than the second-generation cephalosporins against certain gram-negative bacteria, such as Streptococcus pneumoniae. They are also more resistant to beta-lactamases, enzymes that can inactivate some cephalosporins.
Choice A is wrong because first-generation cephalosporins have less activity against gram-negative bacteria and are more susceptible to beta-lactamases.
Choice B is wrong because second-generation cephalosporins have less activity against Streptococcus pneumoniae than third-generation cephalosporins, and are also less resistant to beta-lactamases.
Choice D is wrong because fourth-generation cephalosporins have a broader spectrum of activity against gram-negative bacteria, including some that are resistant to third-generation cephalosporins, but they are not more effective against Streptococcus pneumoniae.