A 22 kg patient has an order for cefazolin 500 mg IV every 6 hours. The safe dose is 50 mg/kg/day. Is the ordered dose safe for the patient?
The Correct Answer is ["No"," the ordered dose is not safe for the patient."]
Calculate the Maximum Safe Daily Dose (mg/day)
Patient weight: 22 kg
Maximum safe dose: 50 mg/kg/day
Maximum Safe Daily Dose = 22 kg x 50 mg/kg/day
= 1,100 mg/day
Calculate the Total Ordered Daily Dose (mg/day)
Ordered dose per administration: 500 mg
Frequency: Every 6 hours (4 doses per day)
Total Ordered Daily Dose = 500 mg/dose x 4 doses/day
= 2,000 mg/day
The Total Ordered Daily Dose (2,000 mg/day) is greater than the Maximum Safe Daily Dose (1,100 mg/day). The ordered dose is unsafe.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Striae gravidarum can appear in the second or third trimester, not exclusively in the third. Their severity is strongly influenced by genetic predisposition, hormonal changes, and the degree of skin stretching rather than fetal growth.
B. Striae gravidarum result from dermal tearing as the skin stretches beyond its elastic capacity. Hormones such as cortisol and estrogen reduce fibroblast activity and collagen strength, predisposing the skin to rupture and forming stretch marks.
C. Striae gravidarum are caused by autoimmune destruction of dermal tissue, commonly seen in There is no autoimmune mechanism involved in the development of striae. They are purely structural and hormonal changes in the skin rather than immune-mediated conditions.
D. Striae actually result from decreased dermal elasticity and collagen integrity. Estrogen and glucocorticoids impair collagen synthesis, leading to thinning and tearing of the dermal layer instead of thickening.
Correct Answer is ["40% to 50%"]
Explanation
A maternal blood volume increase of approximately 40% to 50% occurs during pregnancy to meet the heightened metabolic demands of the mother and fetus. This expansion enhances uteroplacental perfusion, compensates for blood loss at delivery, and maintains adequate circulation despite reduced systemic vascular resistance. The increased plasma volume also contributes to physiologic anemia of pregnancy due to hemodilution but is essential for sustaining optimal fetal oxygenation and nutrient transport.
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