A nurse is administering enoxaparin, a low-molecular-weight heparin, to a client who has undergone orthopedic surgery. The nurse should administer this medication by which route and at which site?

Intramuscular injection in the deltoid muscle

Subcutaneous injection in the abdomen

Intravenous infusion in a peripheral vein

Intradermal injection in the forearm.

Answer and Explanation

The Correct Answer is B

Subcutaneous injection in the abdomen. This is because enoxaparin is a low-molecular-weight heparin that is administered subcutaneously, usually in the abdomen or outer thigh. The drug should be clear and colorless or pale yellow. The dosage for adults is typically 30mg every 12 hours for 7 to 10 days, or 40mg once a day for 3 weeks after hip replacement surgery. The needle should be inserted fully into the skin and the syringe plunger should be pressed down to inject the drug. Injection sites should be rotated and areas of active skin disease or injury should be avoided.

Choice A is wrong because intramuscular injection in the deltoid muscle is not the recommended route or site for enoxaparin. Intramuscular injection may cause bleeding, bruising, or hematoma formation.

Choice C is wrong because intravenous infusion in a peripheral vein is not the recommended route for enoxaparin. Enoxaparin can be given intravenously only as a bolus injection for acute coronary syndrome, not as an infusion.

Choice D is wrong because intradermal injection in the forearm is not the recommended route or site for enoxaparin. Intradermal injection may cause skin irritation, infection, or necrosis.

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Free Nursing Study Resources

Correct Answer is A

Explanation

Omeprazole, a proton pump inhibitor, is contraindicated with cilostazol, an antiplatelet drug, for intermittent claudication.

This is because omeprazole can inhibit the metabolism of cilostazol by affecting the hepatic/intestinal enzyme CYP2C19, which is responsible for converting cilostazol to its active metabolites.This can result in increased plasma levels of cilostazol and increased risk of bleeding and adverse effects.

Choice B is wrong because metoprolol, a beta blocker, is not contraindicated with cilostazol.

Metoprolol can be used to treat hypertension, angina, and heart failure, which are common comorbidities in patients with intermittent claudication.Metoprolol does not interact significantly with cilostazol or affect its metabolism.

Choice C is wrong because simvastatin, a statin, is not contraindicated with cilostazol.

Simvastatin can be used to lower cholesterol and prevent cardiovascular events in patients with intermittent claudication.Simvastatin does not interact significantly with cilostazol or affect its metabolism.

Choice D is wrong because glyburide, a sulfonylurea, is not contraindicated with cilostazol.

Glyburide can be used to treat type 2 diabetes mellitus, which is a common risk factor for intermittent claudication.Glyburide does not interact significantly with cilostazol or affect its metabolism.

A. “You should avoid taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) while on this medication.” B. “You should report any signs of bleeding, such as nosebleeds, bruising, or black stools, to your provider.” C. “You should take this medication with food to prevent gastrointestinal upset.” D. “You should have your blood pressure checked regularly while on this medication.” E. “You should stop taking this medication at least 5 days before any planned surgery.”.

Correct Answer is ["A","B","E"]

Explanation

Clopidogrel is an antiplatelet drug that inhibits the ability of platelets to clump together as part of a blood clot.It is used to prevent recurrent stroke and other cardiovascular events in people who are at high risk.

Choice A is correct because taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) while on clopidogrel can increase the risk of bleeding.These drugs also affect platelet function and can interfere with the action of clopidogrel.

Choice B is correct because bleeding is the most common side effect of clopidogrel.Any signs of bleeding, such as nosebleeds, bruising, or black stools, should be reported to the provider as they may indicate a serious complication.

Choice C is wrong because clopidogrel can be taken with or without food.Taking it with food does not prevent gastrointestinal upset, which is another possible side effect of clopidogrel.

Choice D is wrong because clopidogrel does not affect blood pressure.However, having high blood pressure can increase the risk of stroke and other cardiovascular events, so it is important to have it checked regularly and treated if necessary.

Choice E is correct because clopidogrel should be stopped at least 5 days before any planned surgery.This is to reduce the risk of excessive bleeding during or after the surgery.The provider should be informed about the use of clopidogrel and any other medications before undergoing any surgical procedure.

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A nurse is administering enoxaparin, a low-molecular-weight heparin, to a client who has undergone orthopedic surgery. The nurse should administer this medication by which route and at which site?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is reviewing the medication history of a client who is prescribed cilostazol, an antiplatelet drug, for intermittent claudication. The nurse should recognize that which of the following medications is contraindicated with cilostazol?

Correct Answer is A

Explanation

A nurse is teaching a client who is prescribed clopidogrel, an antiplatelet drug, to prevent recurrent stroke. Which of the following statements should the nurse include in the teaching? (Select all that apply.)

Correct Answer is ["A","B","E"]

Explanation

A nurse is preparing to administer alteplase, a thrombolytic drug, to a client who has an acute myocardial infarction. The nurse knows that this drug works by which mechanism?

A nurse is administering enoxaparin, a low-molecular-weight heparin, to a client who has undergone orthopedic surgery. The nurse should administer this medication by which route and at which site?

A nurse is caring for a client who has a history of coronary thrombosis and is taking warfarin as a long-term anticoagulant therapy. What laboratory test should the nurse monitor to evaluate the effectiveness of warfarin?