A nurse is assessing a client who has hypercholesterolemia and is receiving simvastatin. Which of the following findings should the nurse recognize as a potential adverse effect?
Blurred vision
Orthostatic hypotension
Urinary retention
Muscle weakness
The Correct Answer is D
Choice A reason: Blurred vision is not a common or serious side effect of simvastatin, as it does not affect the eyes or the vision. Blurred vision may be caused by other factors, such as diabetes, hypertension, or eye disorders.
Choice B reason: Orthostatic hypotension is not a common or serious side effect of simvastatin, as it does not affect the blood pressure or the vascular tone. Orthostatic hypotension may be caused by other factors, such as dehydration, anemia, or medication interactions.
Choice C reason: Urinary retention is not a common or serious side effect of simvastatin, as it does not affect the urinary tract or the bladder function. Urinary retention may be caused by other factors, such as prostate enlargement, infection, or nerve damage.
Choice D reason: Muscle weakness is a common and serious side effect of simvastatin, as it can indicate muscle damage or rhabdomyolysis. Rhabdomyolysis is a life-threatening condition that causes the breakdown of muscle tissue and the release of myoglobin into the bloodstream, which can lead to kidney failure. Muscle weakness may be accompanied by muscle pain, tenderness, or dark urine. The nurse should monitor the client's creatine kinase (CK) levels and report any signs of muscle damage to the provider.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: "I'll be sure to eat more foods with vitamin K." is not the correct statement. Vitamin K is a nutrient that helps the blood to clot. Warfarin is an anticoagulant that inhibits the action of vitamin K and prevents the formation of blood clots. Eating more foods with vitamin K can counteract the effect of warfarin and increase the risk of thrombosis. The client should maintain a consistent intake of vitamin K and avoid sudden changes in their diet.
Choice B reason: "I'll take aspirin for my headaches." is not the correct statement. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits platelet aggregation and prolongs bleeding time. Taking aspirin with warfarin can increase the risk of bleeding and bruising. The client should avoid taking any NSAIDs without consulting their provider. The client should use acetaminophen or other non-NSAID pain relievers for their headaches.
Choice C reason: "I'll use my electric razor for shaving." is the correct statement. Using an electric razor for shaving can reduce the risk of cuts and bleeding. The client should avoid using sharp objects or instruments that can cause injury or trauma. The client should also use a soft toothbrush and floss gently to prevent bleeding gums.
Choice D reason: "It's okay to have a couple of glasses of wine with dinner each evening." is not the correct statement. Alcohol can interact with warfarin and affect its metabolism and effectiveness. Drinking alcohol with warfarin can either increase or decrease the blood levels of warfarin and alter the international normalized ratio (INR), which is a measure of the blood's clotting ability. The client should limit their alcohol intake and monitor their INR regularly.
Correct Answer is D
Explanation
Choice A reason: Using IV tubing specific for heparin sodium when administering the infusion is not the correct action. Heparin sodium can be administered using any standard IV tubing, as long as it is primed with heparin solution to prevent clotting in the tubing.
Choice B reason: Administering 50,000 units of heparin by IV bolus every 12 hours is not the correct action. This is a very high dose of heparin that can cause bleeding complications. The usual dose of heparin for continuous IV infusion is 15 to 25 units/kg/hour, adjusted according to the aPTT results.
Choice C reason: Having vitamin K available on the nursing unit is not the correct action. Vitamin K is the antidote for warfarin, not heparin. Vitamin K reverses the effects of warfarin by increasing the synthesis of clotting factors in the liver.
Choice D reason: Checking the activated partial thromboplastin time (aPTT) every 4 hours is the correct action. The aPTT is a blood test that measures the time it takes for the blood to clot. It is used to monitor the effectiveness and safety of heparin therapy. The therapeutic range of aPTT for heparin is 1.5 to 2.5 times the normal value, or 60 to 80 seconds. The nurse should check the aPTT every 4 hours until it is within the therapeutic range, and then every 6 to 8 hours thereafter. The nurse should adjust the heparin infusion rate according to the aPTT results and the prescriber's orders.
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