A nurse is caring for a client who is prescribed cyclosporine following a kidney transplant. The nurse should instruct the client that which of the following foods can increase cyclosporine levels to a toxic level?
Orange juice
Bananas
Grapefruit juice
Smoked salmon
The Correct Answer is C
A. Orange juice: Does not affect cyclosporine metabolism.
B. Bananas: No known interaction with cyclosporine.
C. Grapefruit juice: Inhibits CYP3A4 enzyme in the liver, which increases cyclosporine levels, leading to toxicity.
D. Smoked salmon: May contain sodium but does not interact with cyclosporine metabolism.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Metformin: When combined with contrast dye, it can increase the risk of lactic acidosis in patients with impaired kidney function; should be held before and after contrast use.
B. Atorvastatin: Though statins are metabolized hepatically, they don’t interact significantly with contrast to increase AKI risk.
C. Carvedilol: Beta-blockers do not interact with contrast dye to cause AKI.
D. Nitroglycerin: Used for angina; not associated with increased AKI risk related to contrast use.
Correct Answer is ["A","C","D","E"]
Explanation
A. Ensure NPO status: The client is kept NPO before the biopsy to reduce the risk of aspiration if sedation is used.
B. Administer diphenhydramine (Benadryl) prior to procedure: This is not routine for kidney biopsy unless the client has allergies or specific indications.
C. Obtain coagulation studies: Important to assess for bleeding risk because kidney biopsies have a high bleeding potential.
D. Verify informed consent: This is essential before any invasive procedure.
E. Collect a urine specimen prior to procedure: A pre-procedure urine sample is collected for baseline comparison.
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