The package insert instructs reconstituting with 3.4 mL of sterile water to yield nafcillin 250 mg/mL. How many mL should the nurse administer?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)
The Correct Answer is ["2"]
Step 1 is to determine the amount of medication in 1 mL after reconstitution. This is calculated by dividing the total available medication (1000 mg) by the total volume after reconstitution (3.4 mL):
1000 mg ÷ 3.4 mL = 294.12 mg/mL
Step 2 is to determine how many mL are needed to obtain 500 mg. This is done by dividing the required dose (500 mg) by the concentration (294.12 mg/mL):
500 mg ÷ 294.12 mg/mL = 1.7 mL
Rounding to the nearest whole number, the correct amount to administer is 2 mL.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale:
The label states to add 3.5 mL of diluent for reconstitution, not 5 mL. So, choice A is incorrect.
Choice B rationale:
After reconstitution, the vial will contain 1 gram of medication, not 500 mg. So, choice B is incorrect.
Choice C rationale:
The label does state to use the solution within 1 hour of reconstitution. So, choice C is correct.
Choice D rationale:
The label states the medication can be used for IM or IV, not only IM. So, choice D is incorrect.
Correct Answer is ["48"]
Explanation
Step 1 is to convert the client’s weight from pounds to kilograms since the medication dosage is prescribed in mg/kg. Given that 1 kg is approximately 2.2 lb, the conversion is:
210 lb ÷ 2.2 = 95.45 kg (rounded to the nearest hundredth).
Step 2 is to calculate the total amount of medication needed using the formula:
Dose (mg/kg) × Weight (kg) = Total medication needed (mg)
5 mg/kg × 95.45 kg = 477.27 mg (rounded to the nearest hundredth).
Step 3 is to calculate the volume to administer using the formula:
Total medication needed (mg) ÷ Concentration (mg/mL) = Volume to administer (mL)
477.27 mg ÷ 10 mg/mL = 47.73 mL
Rounding off to the nearest whole number, the nurse should administer 48 mL of gentamicin.
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