A nurse is preparing to discharge a client newly diagnosed with peptic ulcer disease. The client's diagnostic test results were positive for H pylori bacteria. The health care provider has ordered the "triple therapy" regimen. Which medications will the nurse educate the client on?

Proton-pump inhibitor, an antibiotic, and bismuth salts

Proton-pump inhibitor and two antibiotics

H2-receptor antagonist and two antibiotics

H2-receptor antagonist, proton-pump inhibitor, and an antibiotic

Answer and Explanation

The Correct Answer is B

A. Proton-pump inhibitor, an antibiotic, and bismuth salts: This combination is used in quadruple therapy, not triple therapy. Bismuth is typically included when patients fail first-line treatment or have contraindications to standard regimens.

B. Proton-pump inhibitor and two antibiotics: Triple therapy involves a proton-pump inhibitor (like omeprazole or lansoprazole) and two antibiotics, commonly clarithromycin and either amoxicillin or metronidazole. This regimen is designed to eradicate H. pylori and promote ulcer healing.

C. H2-receptor antagonist and two antibiotics: H2-receptor antagonists like ranitidine are not part of the standard triple therapy. They are less effective than PPIs in suppressing gastric acid and are not the preferred first-line treatment with antibiotics.

D. H2-receptor antagonist, proton-pump inhibitor, and an antibiotic: This combination is incorrect for triple therapy. Using both an H2-receptor antagonist and a PPI is redundant and not evidence-based. Triple therapy requires a PPI and two antibiotics, not one.

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Correct Answer is B

Explanation

A. Abdominal pain and abnormal liver function tests are expected effects: While rare side effects like abdominal discomfort or liver enzyme elevations can occur, they are not expected or common. Clients should report such symptoms promptly.

B. The medication is to be swallowed whole and taken before meals: Delayed-release PPIs (e.g., omeprazole, lansoprazole) must be swallowed whole to preserve the enteric coating that protects the drug from stomach acid. They should be taken before meals for optimal acid suppression when the proton pumps are most active.

C. May cause proctitis: Proctitis (inflammation of the rectum) is not a recognized side effect of oral proton pump inhibitors. This side effect is unrelated to PPI therapy and is more often associated with infections, radiation, or inflammatory bowel diseases.

D. Do not take with alcohol or any other CNS depressants: PPIs do not have CNS depressant effects and do not interact significantly with alcohol or CNS depressants. While limiting alcohol is generally advisable for gastrointestinal health, it is not specific to PPI use.

A. Abdominal pain B. Infection C. Diarrhea D. Constipation

Correct Answer is C

Explanation

A. Abdominal pain: Loperamide is not indicated for isolated abdominal pain and may actually worsen symptoms if used inappropriately, especially if the pain is related to a bowel obstruction or inflammatory condition.

B. Infection: While diarrhea may accompany infection, loperamide is typically avoided in infectious diarrhea, especially when caused by bacteria or toxins, because it can delay pathogen clearance and worsen the illness.

C. Diarrhea: Loperamide is an antidiarrheal agent that slows intestinal motility, allowing more fluid absorption in the colon. It is commonly prescribed PRN for symptomatic relief of non-infectious diarrhea.

D. Constipation: Administering loperamide in the setting of constipation would exacerbate the condition. It further reduces bowel motility, increasing the risk of fecal impaction or ileus.

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A nurse is preparing to discharge a client newly diagnosed with peptic ulcer disease. The client's diagnostic test results were positive for H pylori bacteria. The health care provider has ordered the "triple therapy" regimen. Which medications will the nurse educate the client on?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is preparing a teaching tool about oral delayed release proton pump inhibitors used to treat duodenal ulcer disease caused by H. pylori. Which statement will the nurse include in their teaching?

Correct Answer is B

Explanation

A client has an order for loperamide as needed (PRN). For which condition would the nurse administer this medication?

Correct Answer is C

Explanation

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