A nurse is providing instruction to a new nurse about caring for clients who are receiving diuretic therapy to treat heart failure.
The nurse should explain that which of the following medications puts clients at risk for both hyperkalemia and hyponatremia?
Furosemide.
Metolazone.
Hydrochlorothiazide.
Spironolactone.
The Correct Answer is D
This question requires applying knowledge of diuretic pharmacology and electrolyte management in heart failure. It identifies the mechanism of action of potassium-sparing diuretics and their specific effect on mineral balance, which is critical for preventing dangerous electrolyte disturbances in patients on chronic therapy.
Choice A rationale
Furosemide is a loop diuretic that inhibits the Na-K-Cl cotransporter in the thick ascending limb of the loop of Henle. It typically causes significant urinary loss of potassium, leading to hypokalemia, not hyperkalemia, in patients on long-term treatment.
Choice B rationale
Metolazone is a thiazide-like diuretic that acts on the distal convoluted tubule. Like other thiazide diuretics, it predominantly causes urinary potassium wasting and sodium excretion, leading to hypokalemia and hyponatremia rather than an increase in serum potassium levels.
Choice C rationale
Hydrochlorothiazide is a thiazide diuretic that acts on the distal convoluted tubule. Its mechanism of action leads to increased distal delivery of sodium, which promotes potassium and sodium excretion in the urine, resulting in hypokalemia and hyponatremia for the patient.
Choice D rationale
Spironolactone is a potassium-sparing diuretic that acts as an aldosterone antagonist in the distal tubule. It inhibits sodium reabsorption and potassium excretion, which can cause hyperkalemia, while its natriuretic effect contributes to potential hyponatremia in vulnerable patient populations.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
This question tests the application of the nursing process phases. It requires identifying the specific stage where the nurse compares the patient's current status and clinical outcomes against the established goals to determine the success of the implemented interventions and the need for plan modifications.
Choice A rationale
The evaluation phase involves comparing the patient’s health status with the goals and outcomes defined in the care plan. Monitoring progress after a new medication regimen is a classic example of evaluating the effectiveness of a planned clinical intervention.
Choice B rationale
The planning phase involves setting measurable goals, outcomes, and nursing interventions based on the assessment data. While the nurse plans for the future, the action of monitoring ongoing progress is an evaluative step, not the creation of the initial care plan.
Choice C rationale
The assessment phase is the collection of patient data, including health history, physical examination, and diagnostic results. Monitoring progress happens after interventions have been initiated, whereas assessment occurs before and during the continuous data collection process to identify patient needs.
Choice D rationale
The implementation phase is the actual execution of nursing interventions and actions. While the nurse performs the monitoring, the cognitive process of determining how well the medication is working by comparing patient status to outcomes is defined as the evaluation phase.
Correct Answer is B
Explanation
This question evaluates the understanding of parenteral drug administration routes. It requires identifying the pharmacological advantages of avoiding the gastrointestinal tract, specifically how parenteral routes bypass initial hepatic metabolism, thereby ensuring greater drug bioavailability compared to drugs that undergo significant first-pass metabolism.
Choice A rationale
Parenteral drugs are administered via routes like IV or IM, avoiding the stomach entirely. Absorption kinetics are not related to gastric contents, as the medication is delivered directly into the systemic circulation or muscle tissue for uptake.
Choice B rationale
The first-pass effect refers to the metabolic breakdown of oral drugs by the liver before they reach systemic circulation. Parenteral routes, such as intravenous administration, bypass this process entirely, allowing the drug to reach target sites without initial hepatic degradation.
Choice C rationale
Stomach pH only affects the absorption of orally administered drugs that must survive the gastric environment and cross the mucosal lining. Parenteral medications are delivered outside of the digestive tract, so gastric pH has no impact on their bioavailability.
Choice D rationale
Parenteral drugs exert systemic effects by circulating through the bloodstream to reach various target tissues and organs throughout the body. They do not depend on the intestines for their action, as they are not administered via the enteral route.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.
