A nurse needs to infuse esmolol to a patient weighing 65 kg. The dose on hand is 2,500 mg esmolol in 250 mL of fluid. The patient requires a dose of 200 mcg/kg/min to control a hypertensive crisis. Which rate should the nurse calculate to infuse this medication? Round to the nearest whole number.

To find the volume of fluid that will be left at 10:00 am, you need to calculate the following:

- The time elapsed in minutes from 8:45 am to 10:00 am using the formula: Time elapsed (min) = End time (min) - Start time (min)
- The volume of fluid infused in milliliters (mL) during the time elapsed using the formula: Volume infused (mL) = Flow rate (mL/min) x Time elapsed (min)
- The volume of fluid left in milliliters (mL) at 10:00 am using the formula: Volume left (mL) = Initial volume (mL) - Volume infused (mL)

First, use the formula for time elapsed to find how many minutes have passed from 8:45 am to 10:00 am:

Time elapsed (min) = End time (min) - Start time (min)

Since the end time is 10:00 am and the start time is 8:45 am, plug in these values into the formula:

Time elapsed (min) = 600 min - 525 min

Simplify and solve for the time elapsed:

Time elapsed (min) = 75 min

Next, use the formula for volume infused to find the amount of fluid infused in milliliters during the time elapsed:

Volume infused (mL) = Flow rate (mL/min) x Time elapsed (min)

Since the flow rate is 2 mL/min and the time elapsed is 75 min, plug in these values into the formula:

Volume infused (mL) = 2 mL/min x 75 min

Simplify and solve for the volume infused:

Volume infused (mL) = 150 mL

Then, use the formula for volume left to find the amount of fluid left in milliliters at 10:00 am:

Volume left (mL) = Initial volume (mL) - Volume infused (mL)

Since the initial volume is 1500 mL and the volume infused is 150 mL, plug in these values into the formula:

Volume left (mL) = 1500 mL - 150 mL

Simplify and solve for the volume left:

Volume left (mL) = 1350 mL

Therefore, the volume of fluid that will be left at 10:00 am is **1350 mL**.

To set the IV pump correctly, you need to calculate the following:

• The patient's weight in kilograms
• The dose of Zofran in milligrams
• The infusion rate in milliliters per hour

First, convert the patient's weight from pounds to kilograms by dividing by 2.2:

176 lb / 2.2 = 80 kg

Next, multiply the patient's weight by the dose of Zofran per kilogram to get the total dose in milligrams:

80 kg x 0.15 mg/kg = 12 mg

Then, use the formula for infusion rate to find how many milliliters per hour the IV pump should deliver:

Infusion rate (mL/h) = (Total volume (mL) x Flow factor (gt/mL)) / Time (min) x 60 min/h

Since the medication is mixed in 50 mL of normal saline and the infusion time is 15 minutes, plug in these values into the formula:

Infusion rate (mL/h) = (50 mL x 1 gt/mL) / 15 min x 60 min/h

Simplify and solve for the infusion rate:

Infusion rate (mL/h) = 200 mL/h