A nurse tells a nursing student that glucocorticoids given for rheumatoid arthritis are nearly identical to substances produced naturally by the body. The student remarks that the drug must be very safe. Which response by the nurse is correct?

"The negative feedback loop prevents side effects."

"As long as the drug is taken as prescribed, side effects usually do not occur."

"By interrupting the inflammatory process, these drugs inhibit side effects."

"Side effects can occur and are dependent on the dose and duration of treatment."

Answer and Explanation

The Correct Answer is D

a) While the negative feedback loop plays a role in the body's natural regulation of corticosteroids, it does not eliminate the potential for side effects when exogenous glucocorticoids are administered.

b) Taking the drug as prescribed does not guarantee the absence of side effects. Side effects are inherent to glucocorticoid therapy and can occur even with appropriate use.

c) Interrupting the inflammatory process does not directly inhibit side effects. The anti inflammatory action is the therapeutic effect, but it does not eliminate the potential for side effects.

d) Glucocorticoids, even those produced naturally by the body, can cause side effects, and the likelihood and severity of these side effects depend on the dose and duration of treatment. Regular monitoring and appropriate management are essential.

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Correct Answer is A

Explanation

a) St. John's Wort is known to increase the risk of bleeding, particularly when used in conjunction with anticoagulant medications. This effect is of concern and may require adjustments in the treatment plan.

b) While St. John's Wort can interact with various drugs, increasing the risk of bleeding is a more immediate concern.

c) St. John's Wort does not counteract the effects of CNS depressants; it may actually enhance the effects of these drugs.

d) St. John's Wort is known to induce the metabolism of some drugs, potentially reducing their effectiveness, but the immediate concern is the risk of bleeding.

A. "My dose should skip the next dose if the medication makes me sleepy." B. "I should take it after my noon meal." C. "I should take it before breakfast on an empty stomach." D. "I should stop taking it if my thyroid-stimulating hormone (TSH) level is high."

Correct Answer is C

Explanation

A) Taking levothyroxine at bedtime may affect sleep, but this statement suggests an incorrect understanding of the dosing schedule.

B) Taking levothyroxine with a meal may interfere with its absorption. The medication is generally recommended to be taken on an empty stomach.

C) Taking levothyroxine before breakfast on an empty stomach is the standard recommendation for optimal absorption.

D) Stopping levothyroxine based on TSH levels should be done under the guidance of a healthcare provider, and it's not a routine approach to medication administration.

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A nurse tells a nursing student that glucocorticoids given for rheumatoid arthritis are nearly identical to substances produced naturally by the body. The student remarks that the drug must be very safe. Which response by the nurse is correct?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is obtaining a history from a client who discloses daily use of St. John's Wort in addition to prescription drugs. Which effect of this dietary supplement would most concern the nurse?

Correct Answer is A

Explanation

Which statement by the client shows a correct understanding of how they should take their levothyroxine?

Correct Answer is C

Explanation

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