A nurse tells a nursing student that glucocorticoids given for rheumatoid arthritis are nearly identical to substances produced naturally by the body. The student remarks that the drug must be very safe. Which response by the nurse is correct?

"The negative feedback loop prevents side effects."

"As long as the drug is taken as prescribed, side effects usually do not occur."

"By interrupting the inflammatory process, these drugs inhibit side effects."

"Side effects can occur and are dependent on the dose and duration of treatment."

Answer and Explanation

The Correct Answer is D

a) While the negative feedback loop plays a role in the body's natural regulation of corticosteroids, it does not eliminate the potential for side effects when exogenous glucocorticoids are administered.

b) Taking the drug as prescribed does not guarantee the absence of side effects. Side effects are inherent to glucocorticoid therapy and can occur even with appropriate use.

c) Interrupting the inflammatory process does not directly inhibit side effects. The anti inflammatory action is the therapeutic effect, but it does not eliminate the potential for side effects.

d) Glucocorticoids, even those produced naturally by the body, can cause side effects, and the likelihood and severity of these side effects depend on the dose and duration of treatment. Regular monitoring and appropriate management are essential.

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Correct Answer is C

Explanation

a) Intravenous trimethoprim/sulfamethoxazole may still induce an adverse reaction, and withholding the oral medication is the more prudent initial action.

b) Administering the dose may worsen the client's condition, and addressing the symptoms requires notifying the provider first.

c) Withholding the treatment and promptly notifying the provider about the observed symptoms is the correct immediate response to potential adverse reactions.

d) Initiating probiotics and tapering off the medication may be considerations, but the urgent action is to withhold the medication and inform the provider.

A. Liver disease B. Gender C. Height D. Age E. Genetic factors

Correct Answer is ["A","C","D","E"]

Explanation

a) Liver disease can affect drug metabolism and clearance, influencing the response to medications.

b) Gender may play a role in drug response, as there are some gender-related differences in drug metabolism and distribution.

c) Height can influence drug dosing, especially for medications with weight-based dosing.

d) Age is a crucial factor in drug response, as the metabolism and elimination of drugs can vary across different age groups.

e) Genetic factors, including variations in drug-metabolizing enzymes and drug receptors, can significantly impact an individual's response to a drug.

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A nurse tells a nursing student that glucocorticoids given for rheumatoid arthritis are nearly identical to substances produced naturally by the body. The student remarks that the drug must be very safe. Which response by the nurse is correct?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Correct Answer is C

Explanation

Which variables can help determine the client's response to a drug? (Select all that apply.)

Correct Answer is ["A","C","D","E"]

Explanation

The nurse is caring for a client who is receiving vancomycin. The nurse notes the client is experiencing flushing, rash, pruritus, and urticaria. The client's heart rate is 120 beats/min, and blood pressure is 92/57 mm Hg. What complication is the client experiencing?

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