A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.
Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?
22 mg
486 mg
44 mg
47 mg
The Correct Answer is C
We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.
BSA = 0.007184 × W^0.425 × H^0.725.
where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725
BSA = 2.15 m².
Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.
Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.
The total dose for 5 days is:.
Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days
Total dose = 215 mg.
Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.
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Related Questions
Correct Answer is B
Explanation
This is the most commonly used method for calculating pediatric doses, especially for medications that are weight-based. The pediatric dose is typically calculated as a fraction or percentage of the adult dose based on the child's weight. For example, if the adult dose is 100mg and the child weighs 50kg, the child's dose may be calculated as 50mg (50% of the adult dose). Actual body weight takes into account the child's current weight, which can be an important factor in determining the appropriate dose.
Reasons why the other choices are not answers:
A. Body surface area is a method for calculating pediatric doses, but it is typically used for medications that are associated with toxicity or have a narrow therapeutic index.
C. Ideal body weight is an estimate of what a person's weight should be based on their height and gender, rather than their actual weight. It may be used in situations where a child is significantly overweight or underweight, but it is rarely used for pediatric dosing.
D. Actual body height is rarely used for pediatric dosing, as it does not take into account the child's weight or other important factors. It may be used in certain situations, such as when dosing growth hormone therapy.
Correct Answer is B
Explanation
To calculate the dose of digoxin in micrograms (mcg) that the child should receive, we need to first convert the weight of the child from pounds to kilograms:.
30 lb / 2.205 = 13.61 kg.
Next, we can calculate the dose of digoxin in mcg:. Dose (in mcg) = Weight (in kg) x Dose (in mcg/kg). Dose (in mcg) = 13.61 kg x 10 mcg/kg.
Dose (in mcg) = 136.1 mcg.
Now we need to calculate the volume of digoxin solution to administer. Since the concentration of the digoxin solution is 1 mg/mL, we can use proportion to calculate the volume:.
1 mg is to 1 mL as 136.1 mcg is to X mL. 1/1 = 136.1/X.
Cross-multiplying, we get:. 1X = 136.1 x 1.
X = 136.1 mL.
Therefore, the nurse should administer 0.1361 mL (136.1 mcg) of digoxin to the child.
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