A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.
Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?
22 mg
486 mg
44 mg
47 mg
The Correct Answer is C
We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.
BSA = 0.007184 × W^0.425 × H^0.725.
where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725
BSA = 2.15 m².
Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.
Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.
The total dose for 5 days is:.
Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days
Total dose = 215 mg.
Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.
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Related Questions
Correct Answer is B
Explanation
To calculate the answer, we can use the following formula:.
(mg of drug required / total mg in vial) x total volume in vial = mL to administer. First, let's convert the dose from mg to g:.
80 mg = 0.08 g.
Next, let's plug in the values:. (0.08 g / 1 g) x 8 mL = 0.64 mL.
Therefore, the nurse should administer 0.64 mL of Solu-Medrol.
Correct Answer is A
Explanation
Dextrose 50%, add 1 mL to 4 mL injectable saline. To obtain 5 mL of 10% dextrose, 0.5 mL of the 50% dextrose should be diluted with 4.5 mL of sterile water or normal saline. Therefore, the nurse should add 1 mL of the 50% dextrose to 4 mL of injectable saline to get a final concentration of 10% dextrose in 5 mL. This will give the client the appropriate dose.
Choice B is incorrect because adding 2 mL of the 50% dextrose to 3 mL of saline would give a final concentration of 20%, which is higher than the prescribed concentration of 10%.
Choice C is incorrect because adding 3 mL of the 50% dextrose to 2 mL of saline would give a final concentration of 30%, which is significantly higher than the prescribed concentration of 10%.
Choice D is incorrect because adding 4 mL of the 50% dextrose to 1 mL of saline would give a final concentration of 40%, which is much higher than the prescribed concentration of 10%.
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