A vial contains 1 gram of medication and the directions for reconstitution indicate: "For IM use, add 4 mL sterile water for injection. Resulting solution contains 250 mg of medication per mL." What is the concentration of the solution after reconstitution?
1 gram
500 mg/ml
4 ml
250 mg/mL
The Correct Answer is D
Calculation:
- Identify the total amount of medication and the total volume after reconstitution
Total Medication: 1 g = 1000 mg
Volume added: 4 mL
- Calculate the concentration
Concentration = Total Medication ÷ Total Volume
Concentration = 1000 ÷ 4
= 250 mg/mL
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is {"dropdown-group-1":"D"}
Explanation
A. Indirectly: Infusion pumps do not control fluid delivery indirectly; they provide precise, direct control over both rate and volume. Indirect regulation would rely on manual estimation or gravity, which lacks accuracy.
B. Manually: Manual regulation involves using roller clamps or gravity drips, which are prone to error and cannot ensure consistent infusion rates. Infusion pumps are specifically designed to minimize manual adjustments.
C. Occasionally: Infusion pumps provide continuous control rather than intermittent or occasional regulation. Sporadic adjustments would defeat the purpose of automated delivery and compromise safety.
D. Automatically: Infusion pumps are engineered to automatically deliver fluids and medications at predetermined rates and volumes, ensuring accuracy and consistency. This reduces the risk of under- or over-infusion and enhances patient safety.
Correct Answer is C
Explanation
A. Hypertonic: Hypertonic solutions have a higher solute concentration than human blood, causing water to move out of cells and leading to cellular shrinkage. These solutions are used in specific clinical situations such as reducing cerebral edema. They do not match normal plasma osmolality.
B. Hyperosmolar: Hyperosmolar refers to a solution with increased total osmoles per liter, which may or may not be equal to blood concentration. This term describes osmotic strength rather than equivalence to plasma. It does not specifically indicate the same solute concentration as blood.
C. Isotonic: Isotonic solutions have the same solute concentration and osmotic pressure as human blood plasma. They do not cause net fluid movement into or out of cells, maintaining normal cell size and function. Common examples include 0.9% normal saline and lactated Ringer’s.
D. Hypotonic: Hypotonic solutions have a lower solute concentration than blood, causing water to move into cells and potentially leading to cellular swelling. These fluids are used cautiously due to the risk of edema. They do not match plasma solute concentration.
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