An 18-year-old male is taking Hydroxyurea for treatment of sickle cell anemia. Which options below indicate this medication is working successfully?
The patient experiences a decrease in hemoglobin S.
The patient experiences dehydration due to diuresis
The patient experiences an increase in fetal hemoglobin (Hbg F)
The patient needs fewer blood transfusions.
The patient experiences diuresis
Correct Answer : C,D
A. The patient experiences a decrease in hemoglobin S. Hydroxyurea does not decrease hemoglobin S levels directly; it works by increasing fetal hemoglobin (Hgb F) levels.
B. The patient experiences dehydration due to diuresis. This is not an indication that Hydroxyurea is working; it is a potential side effect that should be monitored.
C. The patient experiences an increase in fetal hemoglobin (Hbg F). Hydroxyurea works by increasing the levels of fetal hemoglobin, which reduces the sickling of red blood cells.
D. The patient needs fewer blood transfusions. Successful treatment with Hydroxyurea should reduce the frequency of vaso-occlusive crises and the need for blood transfusions.
E. The patient experiences diuresis. This is not an indicator of the medication's effectiveness; it is a potential side effect.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","D","E"]
Explanation
A. Feeling for changes in the underarm area is important as breast tissue extends into this region and lumps can form there.
B. Since menopausal women do not have periods, they can perform BSE at any consistent time each month to help remember to do it regularly.
C. Pressing the breasts too firmly could cause discomfort and is not necessary for detecting lumps.
D. Performing BSE in the shower is effective because the soapy water allows the fingers to move smoothly over the skin.
E. Using fingertips is the proper technique for checking breasts, as it allows for more sensitivity in detecting changes in the breast tissue.
Correct Answer is D
Explanation
A. Skin color: While changes in skin color can occur in hemochromatosis due to excess iron deposition, it is not the most important parameter to monitor for the effectiveness of deferoxamine.
B. Liver function: Liver function tests can be abnormal in hemochromatosis due to iron overload, but monitoring liver function alone may not adequately assess the effectiveness of deferoxamine in reducing iron levels.
C. Hematocrit: Hematocrit measures the proportion of blood that is made up of red blood cells and may be elevated in hemochromatosis, but it is not the primary parameter to monitor the effectiveness of deferoxamine.
D. Serum iron level: Serum iron level is the most direct indicator of iron overload and the effectiveness of deferoxamine in chelating and removing excess iron from the body.
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