An 18-year-old male is taking Hydroxyurea for treatment of sickle cell anemia. Which options below indicate this medication is working successfully?
The patient experiences a decrease in hemoglobin S.
The patient experiences dehydration due to diuresis
The patient experiences an increase in fetal hemoglobin (Hbg F)
The patient needs fewer blood transfusions.
The patient experiences diuresis
Correct Answer : C,D
A. The patient experiences a decrease in hemoglobin S. Hydroxyurea does not decrease hemoglobin S levels directly; it works by increasing fetal hemoglobin (Hgb F) levels.
B. The patient experiences dehydration due to diuresis. This is not an indication that Hydroxyurea is working; it is a potential side effect that should be monitored.
C. The patient experiences an increase in fetal hemoglobin (Hbg F). Hydroxyurea works by increasing the levels of fetal hemoglobin, which reduces the sickling of red blood cells.
D. The patient needs fewer blood transfusions. Successful treatment with Hydroxyurea should reduce the frequency of vaso-occlusive crises and the need for blood transfusions.
E. The patient experiences diuresis. This is not an indicator of the medication's effectiveness; it is a potential side effect.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Schilling test. The symptoms described are suggestive of pernicious anemia, which is typically diagnosed through a Schilling test to assess vitamin B12 absorption.
B. Erythrocyte Indices. Erythrocyte indices are used to evaluate various aspects of red blood cell characteristics and are not specific to diagnosing pernicious anemia.
C. Bone Marrow Biopsy. While bone marrow biopsy may be used to diagnose certain types of anemia, it is not the primary diagnostic test for pernicious anemia.
D. Radiologic Studies. Radiologic studies are not typically used in the diagnosis of pernicious anemia.
Correct Answer is D
Explanation
A. Multiple hospitalizations for COPD are not a direct contraindication for HRT, although respiratory health should be monitored.
B. Concurrent treatment for GERD is not a contraindication for HRT.
C. History of dermatitis does not contraindicate the use of HRT.
D. History of breast cancer is a significant contraindication for HRT due to the potential for hormone therapy to stimulate the growth of hormone-sensitive cancer cells.
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