Cannabinoids such as dronabinol have been used in patients receiving chemotherapy. What is main reason for their use?

A. The bioavailability is usually lower compared to the enteral route: Parenteral administration bypasses the gastrointestinal tract and first-pass metabolism, resulting in higher bioavailability. Drugs administered parenterally typically reach systemic circulation more completely and predictably.

B. The onset of action is usually slower compared to the enteral route: Parenteral routes, such as intravenous or intramuscular injections, generally have a faster onset of action since the medication is delivered directly into the bloodstream or absorbed rapidly from tissues.

C. This route of administration cannot be used for unconscious clients: Parenteral administration is often ideal for unconscious or uncooperative clients because it does not rely on swallowing or gastrointestinal function, allowing rapid and reliable drug delivery.

D. The medication should be prepared using aseptic techniques: Because parenteral drugs are administered through injection, they bypass the body’s natural barriers to infection. Aseptic technique is essential to prevent contamination and minimize the risk of introducing pathogens.

A. Insulin lispro begins reducing blood sugar levels within 15 minutes of administration: Onset of action refers to the time it takes for a drug to produce its first measurable therapeutic effect. In this case, insulin lispro starts lowering blood glucose within 15 minutes.

B. A minimum of 10 units of insulin lispro must be injected to have a therapeutic effect: This describes the minimum effective dose required for a therapeutic response, not the time it takes for the medication to begin working. Dose relates to potency and individual response rather than onset.

C. Insulin lispro has the greatest effect on blood sugar levels 60 minutes after administration: This represents the peak action of the medication the point at which the drug concentration and effect are at their highest not the onset of its action.

D. The effects of insulin lispro wear off approximately 5 hours after administration: This describes the duration of action, or how long the drug continues to produce a therapeutic effect, rather than the time it first begins to act.