Montelukast sodium belongs to which of the following therapeutic class(es)?
Antiasthmatic, Antiallergy
COPD Agent, Antiallergy
Antiasthmatic, COPD Agent
Antiallergy, Antiviral
The Correct Answer is A
A. Montelukast sodium is classified as a leukotriene receptor antagonist. It selectively binds to cysteinyl leukotriene type 1 receptors to inhibit physiological effects of leukotrienes. This prevents airway edema, smooth muscle contraction, and inflammatory responses in asthma and allergic rhinitis.
B. This agent is not a primary COPD agent as it does not sufficiently address the fixed airflow obstruction or chronic bronchitis characteristic of that disease. While it has antiallergy properties, it is not indicated as a first-line treatment for COPD.
C. While montelukast is an antiasthmatic, it is not FDA-approved as a primary COPD agent. Guidelines for chronic obstructive pulmonary disease prioritize long-acting bronchodilators and muscarinic antagonists over leukotriene modifiers. It lacks efficacy in treating non-allergic chronic obstructive lung pathologies.
D. Montelukast is an antiallergy medication, but it possesses no antiviral activity. It does not inhibit viral replication, entry, or protein synthesis within host cells. It is exclusively used for managing inflammatory airway diseases and is never indicated for viral infections.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Rizatriptan is the active pharmaceutical ingredient for the brand Maxalt. While it belongs to the same selective 5-hydroxytryptamine 1B and 1D receptor agonist class, it is not the chemical constituent of Imitrex. It possesses a different pharmacokinetic profile.
B. Almotriptan is the generic name for the brand Axert. This compound is indicated for the acute treatment of migraine with or without aura in adults. It is a separate molecular entity from the drug requested in the question stem.
C. Sumatriptan is the generic name for Imitrex, the first triptan developed for clinical use. It acts as a selective agonist at vascular 5-HT1B and 5-HT1D receptors. This binding induces cranial vessel vasoconstriction and inhibits the release of proinflammatory neuropeptides.
D. Eletriptan is marketed under the brand name Relpax. It is a second-generation triptan used for migraine abortive therapy. It is not the active ingredient in Imitrex. Its metabolism and bioavailability differ significantly from those of sumatriptan.
Correct Answer is ["C","D"]
Explanation
A. Antiallergy medications generally include antihistamines or mast cell stabilizers that target the early-phase allergic response. While the corticosteroid component reduces inflammation, this combination is specifically indicated for chronic respiratory pathologies. It is not classified as a primary antiallergy agent.
B. Bronchoconstrictors represent a pharmacological class that narrow the airways, which is the opposite effect of this medication. Formoterol acts as a long-acting beta-2 agonist to induce smooth muscle relaxation. This drug combination is intended to treat, not cause, bronchoconstriction.
C. COPD agent is a correct classification as this combination is FDA-approved for the maintenance treatment of airflow obstruction in chronic obstructive pulmonary disease. The long-acting bronchodilator ensures sustained patency of the airways. The corticosteroid component helps reduce the associated chronic inflammation.
D. Antiasthmatic is a correct therapeutic class because this combination targets the underlying inflammation and bronchoconstriction in asthma. Budesonide reduces airway hyperresponsiveness through glucocorticoid receptor activation. Formoterol provides long-acting bronchodilation to prevent nocturnal and exercise-induced symptoms.
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