On the oxyhemoglobin dissociation curve, what is a cause of a right shift?
Increased heart rate
decreased 2,3DPG
decreased temperature
Increased CO2
The Correct Answer is D
A. Increased heart rate: Heart rate affects cardiac output but does not directly shift the oxyhemoglobin dissociation curve. It influences oxygen delivery to tissues but is not a cause of right- or leftward shifts in hemoglobin’s oxygen affinity.
B. Decreased 2,3-DPG: Lower levels of 2,3-DPG increase hemoglobin’s affinity for oxygen, causing a left shift on the dissociation curve. This makes oxygen unloading at the tissues more difficult rather than promoting a right shift.
C. Decreased temperature: Lower temperature enhances hemoglobin’s affinity for oxygen, resulting in a leftward shift of the curve. Oxygen is held more tightly by hemoglobin, which is opposite of a right shift.
D. Increased CO2: Elevated CO2 levels reduce hemoglobin’s affinity for oxygen, promoting oxygen release to the tissues. This effect, part of the Bohr effect, causes a rightward shift of the oxyhemoglobin dissociation curve, facilitating tissue oxygenation during conditions like hypercapnia or acidosis.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. "I will keep my oxygen tanks away from heat sources": Heat and open flames can pose a significant fire hazard around oxygen, so keeping tanks away from heat sources is essential.
B. "I can smoke as long as I turn off my oxygen first.": Smoking around oxygen is extremely dangerous due to the risk of fire and explosion. Oxygen supports combustion even when the tank is off, so this statement indicates a need for further education on fire safety.
C. "I need to post 'No Smoking' signs in my home.": Posting no-smoking signs is an appropriate safety measure to alert others and reduce the risk of accidental ignition near oxygen sources.
D. "I should store my oxygen tanks upright to prevent tipping": Storing oxygen tanks upright is correct and prevents accidental falls, which could damage the tank or valve.
Correct Answer is A
Explanation
A. Blurred vision: Oxygen toxicity, especially from prolonged exposure to high concentrations of oxygen, can affect the eyes and central nervous system. Blurred vision is a recognized early symptom of CNS oxygen toxicity and indicates the need to reduce oxygen exposure.
B. Low oxygen saturation (SpO2): Low SpO2 indicates hypoxemia, not oxygen toxicity. Oxygen toxicity occurs when oxygen levels are excessively high, not when they are low.
C. Joint pain: Joint pain is not associated with oxygen toxicity. It is unrelated to oxygen therapy and would prompt evaluation for other causes.
D. Low hemoglobin level: Hemoglobin levels reflect oxygen-carrying capacity, not toxicity from oxygen administration. Oxygen toxicity is linked to cellular and tissue damage from high oxygen partial pressures rather than hemoglobin deficiency.
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