The concept of PANDAS is related to which of the following conditions:
OCD
Schizophrenia
Autism
Depression
The Correct Answer is A
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) is a post-infectious syndrome where group A β-hemolytic Streptococcus triggers autoimmune neuroinflammation affecting basal ganglia circuits. This results in sudden-onset obsessive-compulsive symptoms and/or motor tics in children. Pathogenesis involves molecular mimicry with antibodies cross-reacting with neuronal tissue, leading to abrupt behavioral changes. Diagnosis is clinical, and management may involve antibiotics, psychiatric intervention, and immune-modulating therapies in severe cases.
Rationale for correct answers
1. The abrupt onset of obsessive-compulsive symptoms following streptococcal infection aligns with autoimmune pathophysiology involving basal ganglia, making this the defining feature of the disorder.
Rationale for incorrect answers
2. Schizophrenia involves chronic psychosis and disorganized thought, not acute postinfectious onset related to group A streptococcal immune responses.
3. Autism spectrum disorder is a developmental neurobehavioral condition present from early childhood and unrelated to infectious autoimmune triggers.
4. Depression is a mood disorder with persistent sadness, unrelated to acute autoimmune mechanisms following bacterial infection.
Take Home Points
- PANDAS presents with sudden-onset OCD or tics following group A streptococcal infection.
- Pathophysiology involves autoimmune cross-reactivity against basal ganglia neurons.
- Diagnosis is clinical and requires temporal relation to infection and neuropsychiatric symptom onset.
- Differential diagnosis includes Tourette syndrome, autoimmune encephalitis, and primary OCD.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Obsessive-compulsive disorder (OCD)is a chronic psychiatric condition marked by intrusive obsessionsand repetitive compulsionsthat aim to reduce anxiety. These compulsions are often rigid and time-consuming, and any disruption to them can provoke significant distress. The disorder is ego-dystonic, meaning the individual recognizes the irrationality of their behaviors but feels compelled to perform them. Treatment involves gradual exposure and response prevention, often supported by SSRIs and cognitive behavioral therapy.
Rationale for correct answers
2.Limiting ritualistic acts abruptly increases anxiety by disrupting the client’s primary coping mechanism. Without gradual desensitization, this approach risks emotional destabilization and noncompliance.
Rationale for incorrect answers
1.Understanding the nature of anxiety is therapeutic and promotes insight. It does not provoke anxiety but rather supports cognitive restructuring.
3.Involving the client in care planning enhances autonomy and reduces anxiety. Collaborative approaches foster trust and therapeutic engagement.
4.Nonjudgmental environments reduce shame and stigma. They are essential for building rapport and do not contribute to increased anxiety.
Take Home Points
- OCD rituals serve as maladaptive coping mechanisms that temporarily relieve anxiety but reinforce obsessive thought patterns.
- Abrupt restriction of compulsions without client preparation can escalate anxiety and hinder therapeutic progress.
- Effective care planning for OCD requires gradual exposure and response prevention, not immediate behavioral suppression.
- OCD must be differentiated from obsessive-compulsive personality disorder, which lacks the ego-dystonic nature and ritualistic distress.
Correct Answer is ["A","C","D","E"]
Explanation
Obsessive-compulsive disorderinvolves persistent, intrusive thoughts or urges (obsessions) and repetitive actions or mental rituals (compulsions) performed to reduce distress. Obsessions are ego-dystonic, meaning they conflict with the person’s values or desires, and they provoke anxiety that fuels compulsive behaviors.
Rationale for correct answers
1.Obsessional thoughts are intrusive, occurring suddenly and disrupting normal thinking patterns without the person’s intent or control.
3.They are recurrent, repeatedly appearing in the person’s mind despite efforts to dismiss them, often leading to significant distress.
4.These thoughts are uncontrollable, arising involuntarily and persisting despite conscious attempts to suppress or replace them.
5.They are unwanted, causing discomfort because they are inconsistent with the individual’s beliefs, values, or desired mental state.
Rationale for incorrect answers
2.They are rarely realistic; most obsessions involve exaggerated, illogical fears or unlikely scenarios rather than accurate assessments of reality.
6.They are not voluntary, as the person does not willingly initiate them and often wishes to avoid or eliminate them.
Take Home Points
- Obsessions in OCD are intrusive, recurrent, uncontrollable, and unwanted thoughts that cause significant distress.
- They are ego-dystonic and differ from normal worries by their irrational and exaggerated nature.
- OCD requires differentiation from psychotic disorders, where intrusive thoughts may align with fixed false beliefs.
- Effective management involves cognitive-behavioral therapy with exposure and response prevention and, in some cases, pharmacologic treatment.
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