The directions for reconstitution of ampicillin sodium for injection are on the drug label. Directions read: "For IM use, add 3.5mL sterile water for injection Resulting solution contains 250 mg ampicillin sodium per mL. The vial contains ampicillin sodium equivalent to 1 gram. Usual adult dosage of ampicillin is 250 mg-500 mg IM every 6 hours." How much diluent is added to the vial to prepare the medication for IM use?
250 mg/ml
500 mg/mL
1mL
35 mL
The Correct Answer is A
A. 3.5 mL: The directions explicitly state: "For IM use, add 3.5mL sterile water for injection". This is the volume of diluent added to reconstitute the powder.
B. 250 mg/mL: This is the resulting concentration after the diluent has been added, not the volume of the diluent itself.
C. 1mL: This volume is too small and is an incorrect interpretation of the label. 1Ml is the volume that contains 250mg of the drug, but it is not the volume of diluent added.
D. 35 mL: This is 10 times the correct amount and is an incorrect reading of the label. Adding this much would severely dilute the medication.
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Related Questions
Correct Answer is D
Explanation
Step 1: Identify the order
- The doctor ordered 640 mg acetaminophen PO STAT.
Step 2: Interpret the supply
- The bottle says 80 mg per ½ teaspoon.
- ½ teaspoon = 2.5 mL.
- So, 80 mg ÷ 2.5 mL = 32 mg per mL.
Step 3: Calculate the volume needed
- Ordered dose = 640 mg.
- Concentration = 32 mg per mL.
- Volume = 640 ÷ 32 = 20 mL.
Correct Answer is C
Explanation
A. Insulin 100 unit:A 100-unit insulin syringe holds up to 100 units (1 mL). While it can technically hold 15 units, it is calibrated in 2-unit increments and is not the most precise option for small doses like 15 units.
B. 1-ML:A 1-mL syringe (often a Tuberculin or TB syringe) is calibrated in milliliters (mL) and hundredths of a milliliter (0.01 mL). Since the order is in units, a TB syringe is only appropriate if a conversion table is used, which is highly discouraged and error-prone for insulin administration.
C. Insulin 50 unit:A 50-unit insulin syringe holds up to 50 units (0.5 mL) and is calibrated in 1-unit increments. It provides the highest level of accuracy for measuring small insulin doses, such as the ordered 15 units, making it the preferred choice over a 100-unit syringe.
D. 3mL:A 3-mL syringe is far too large and is calibrated in milliliters (0.1 mL increments). It cannot accurately measure a dose as small as 15 units of insulin.
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