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The healthcare provider prescribes interferon beta-1b 0.0625 mg SUBQ every other day for a client with multiple sclerosis. The nurse reconstitutes the single-use vial of powder labeled, "0.3 mg with 1.2 mL of sterile water." How many mL should the nurse administer to the client? (Enter the numerical value only. If rounding is required, round to the nearest hundredth.)
Answer and Explanation

The Correct Answer is ["0.25"]

Here's how to calculate the volume the nurse should administer after reconstituting the medication:

Reconstitution:

The medication vial is labeled "0.3 mg with 1.2 mL of sterile water." This means adding 1.2 mL of diluent will result in a total volume of 1.2 mL solution.

 

Important Note:

The concentration of the medication after reconstitution is not explicitly provided on the label.

We cannot directly calculate the volume to administer based solely on the prescribed dose (0.0625 mg) and the unknown concentration.

Scenario:

In real-world practice, nurses rely on the medication information sheet or the manufacturer's label for dilution instructions and the final concentration after reconstitution.

This information is crucial for calculating the accurate volume to administer the prescribed dose.

Assuming the medication information sheet specifies:

After reconstitution with 1.2 mL diluent, the final concentration is 0.25 mg/mL. 

 

Calculation (based on the assumed concentration):

Prescribed dose: 0.0625 mg

Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)

Volume to administer (mL) = 0.0625 mg / 0.25 mg/mL

Volume to administer (mL) = 0.25 mL (round to nearest hundredth)

Therefore, based on the assumed concentration after reconstitution (0.25 mg/mL), the nurse should administer 0.25 mL to the client.


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Related Questions

Correct Answer is ["0.4"]

Explanation

here's how to calculate the volume (mL) of ketorolac the nurse should administer:

1. Dose of ketorolac to administer:

Dose = 12 mg (given)

2. Concentration of ketorolac in the vial:

Concentration = 30 mg/mL (given)

3. We need to find the volume (mL) containing the prescribed dose (12 mg) considering the concentration (30 mg/mL) in the vial.

Volume to administer (mL): Dose (mg) / Concentration (mg/mL)

Volume to administer (mL): 12 mg / 30 mg/mL

Volume to administer (mL) = 0.4 mL (round to nearest tenth)

Therefore, the nurse should administer approximately 0.4 mL of ketorolac intravenously.

Correct Answer is ["18"]

Explanation

Here's how to calculate the infusion rate (mL/hour) for the nurse to administer furosemide 60 mg IV every 12 hours:

1. Furosemide dose per administration:

Dose = 60 mg (given)

2. Dosage frequency (conversion from hours to minutes):

Frequency (minutes) = 12 hours/dose * 60 minutes/hour

Frequency (minutes) = 720 minutes/dose

3. Medication concentration:

Concentration = 10 mg/mL (given)

4. Infusion duration:

Duration = 20 minutes (given)

5. We need to find the total volume (mL) of the medication to be delivered and then convert that volume to a rate per hour (mL/hour).

Steps:

a. Calculate the volume to be infused (mL):

Volume (mL) = Dose (mg) / Concentration (mg/mL)

Volume (mL) = 60 mg / 10 mg/mL

Volume (mL) = 6 mL

b. Convert infusion duration from minutes to hours:

Infusion time (hours) = Infusion time (minutes) / 60 minutes/hour

Infusion time (hours) = 20 minutes / 60 minutes/hour

Infusion time (hours) = 1/3 hour

c. Calculate the infusion rate (mL/hour):

Infusion rate (mL/hour) = Volume (mL) / Infusion time (hours)

Infusion rate (mL/hour) = 6 mL / (1/3 hour)

Infusion rate (mL/hour) = 18 mL/hour

Therefore, the nurse should set the infusion pump to deliver approximately 18 mL/hour.

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