The healthcare provider prescribes interferon beta-1b 0.0625 mg SUBQ every other day for a client with multiple sclerosis. The nurse reconstitutes the single-use vial of powder labeled, "0.3 mg with 1.2 mL of sterile water." How many mL should the nurse administer to the client? (Enter the numerical value only. If rounding is required, round to the nearest hundredth.)
The Correct Answer is ["0.25"]
Here's how to calculate the volume the nurse should administer after reconstituting the medication:
Reconstitution:
The medication vial is labeled "0.3 mg with 1.2 mL of sterile water." This means adding 1.2 mL of diluent will result in a total volume of 1.2 mL solution.
Important Note:
The concentration of the medication after reconstitution is not explicitly provided on the label.
We cannot directly calculate the volume to administer based solely on the prescribed dose (0.0625 mg) and the unknown concentration.
Scenario:
In real-world practice, nurses rely on the medication information sheet or the manufacturer's label for dilution instructions and the final concentration after reconstitution.
This information is crucial for calculating the accurate volume to administer the prescribed dose.
Assuming the medication information sheet specifies:
After reconstitution with 1.2 mL diluent, the final concentration is 0.25 mg/mL.
Calculation (based on the assumed concentration):
Prescribed dose: 0.0625 mg
Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)
Volume to administer (mL) = 0.0625 mg / 0.25 mg/mL
Volume to administer (mL) = 0.25 mL (round to nearest hundredth)
Therefore, based on the assumed concentration after reconstitution (0.25 mg/mL), the nurse should administer 0.25 mL to the client.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["4.7"]
Explanation
Here's how to calculate the volume (mL) of the reconstituted ampicillin solution the nurse should administer for each dose:
1. We know the following:
Prescribed dose: 140 mg ampicillin (given)
Vial information:
Contains 250 mg ampicillin powder (given)
Reconstituted with 8.3 mL sterile normal saline (given)
Yields a final concentration of 30 mg/mL (given)
2. We need to find the volume (mL) of the reconstituted solution containing the prescribed dose (140 mg) considering the final concentration (30 mg/mL).
Steps:
a. Don't consider the initial volume (8.3 mL) of sterile normal saline. The final concentration (30 mg/mL) refers to the concentration in the diluted solution after adding the saline.
b. Use the following formula:
Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)
c. Plug in the values:
Volume to administer (mL) = 140 mg / 30 mg/mL
Volume to administer (mL) = 4.67 mL (round to nearest tenth)
Therefore, the nurse should administer approximately 4.7 mL of the reconstituted ampicillin solution intravenously every 8 hours for the child.
Correct Answer is ["21"]
Explanation
Here's how to calculate the infusion rate (gtt/min) for the nurse to regulate:
1. We know:
Total volume of D5W solution: 2 L (liters)
Infusion time: 24 hours
IV administration set gtt/mL: 15 gtt/mL
2. We need to find the infusion rate in gtt/min.
Steps:
a. Convert liters to milliliters (mL) for better calculation:
1 liter = 1000 mL
Total volume (mL) = 2 L * 1000 mL/L
Total volume (mL) = 2000 mL
b. Convert infusion time from hours to minutes:
Infusion time (minutes) = Infusion time (hours) x Minutes per hour
Infusion time (minutes) = 24 hours * 60 minutes/hour
Infusion time (minutes) = 1440 minutes
c. Calculate the total volume of solution to be infused per minute:
Volume rate (mL/min) = Total volume (mL) / Infusion time (minutes)
Volume rate (mL/min) = 2000 mL / 1440 minutes
Volume rate (mL/min) = 1.389 mL/min (round to nearest hundredth)
d. Finally, calculate the infusion rate in gtt/min:
Infusion rate (gtt/min) = Volume rate (mL/min) x gtt/mL
Infusion rate (gtt/min) = 1.389 mL/min * 15 gtt/mL
Infusion rate (gtt/min) = 20.835 gtt/min (round to nearest whole number as requested)
Therefore, the nurse should regulate the infusion at approximately 21 gtt/min
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