The medication administration record (MAR) includes an order for glycopyrrolate oral solution 2 mg twice daily PO. The medication drawer contains glycopyrrolate oral solution labeled "1 mg/5 mL."Which of the following is the correct setup for the drug dosage calculation?
2 mg: 2:: 1 mg: x
2 mg: x mL:: 5 mL: 1 mg
1 mg: 5 mL :: 2 mg: x mL
5 mL: 1 mg:: 2 mg: x mL
The Correct Answer is C
A. 2 mg: 2 :: 1 mg: x: This setup is incorrect because it compares the prescribed dose to itself, rather than relating the known concentration of the medication to the desired dose.
B. 2 mg: x mL :: 5 mL: 1 mg: This proportion incorrectly places the known concentration on the right side and the desired dose on the left, making the calculation confusing and prone to error.
C. 1 mg: 5 mL :: 2 mg: x mL: This setup correctly compares the known concentration (1 mg per 5 mL) to the prescribed dose (2 mg) using a proportion. Solving for x gives the accurate volume to administer.
D. 5 mL: 1 mg :: 2 mg: x mL: This setup inverts the known concentration, placing volume before dose, which can lead to miscalculation. Correct proportional setup keeps the dose first and volume second.
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Related Questions
Correct Answer is C
Explanation
A. Administer extended-release tablets once a day: While extended-release formulations are often given once daily, the exact frequency must be confirmed with the prescriber’s order. The label alone does not specify the dosing schedule.
B. Instruct the patient to chew the tablet slowly: Extended-release tablets are formulated to release the drug over time. Chewing them can destroy the coating and cause rapid absorption, increasing the risk of adverse effects.
C. Instruct the patient to swallow the entire tablet: Swallowing the extended-release tablet whole ensures that the medication is released gradually as designed. This maintains therapeutic levels and reduces the risk of toxicity.
D. Crush and dissolve the tablet in 15 mL of water: Crushing or dissolving an extended-release tablet disrupts the controlled-release mechanism, potentially leading to overdose and loss of efficacy.
Correct Answer is B
Explanation
Calculation:
Given dose = 325 mg
Conversion factor: 1 gram (g) = 1,000 milligrams (mg)
- Calculate the dose in grams (g).
Dose (g) = (Dose in mg / Conversion factor)
= (325 mg / 1,000 mg/g)
= 0.325 g.
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