The nurse caring for patients with gastrointestinal disorders would understand which category best describes the mechanism of action of pantoprazole (Protonix)?
Histamine receptor blocker.
Mucosal barrier fortifier.
Proton pump inhibitor.
Stool softener.
The Correct Answer is C
Choice A rationale
Histamine receptor blockers, also known as H2 blockers, inhibit the action of histamine at the parietal cells' H2 receptors, reducing acid production. Examples include famotidine (Pepcid) and ranitidine (Zantac). While they also reduce stomach acid, this is a different mechanism of action from pantoprazole, which works directly on the proton pump.
Choice B rationale
Mucosal barrier fortifiers, such as sucralfate (Carafate), work by creating a protective gel-like coating over ulcers and erosions in the gastrointestinal tract. This barrier protects the damaged tissue from further erosion by stomach acid and pepsin, promoting healing. This mechanism is distinct from how pantoprazole functions to reduce acid secretion.
Choice C rationale
Pantoprazole is classified as a proton pump inhibitor (PPI). Its mechanism of action involves irreversibly binding to and inhibiting the hydrogen-potassium adenosine triphosphatase ($H^+/K^+$ ATPase) enzyme system, or proton pump, located in the gastric parietal cells. This enzyme is responsible for the final step in the secretion of gastric acid, thereby effectively blocking acid production.
Choice D rationale
Stool softeners, or emollient laxatives, work by allowing more water and fat to penetrate the stool, making it softer and easier to pass. A common example is docusate sodium (Colace). Their action is on the large intestine to relieve constipation and is not related to the reduction of gastric acid secretion.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Numbness and tingling around the mouth, or perioral paresthesia, is a classic sign of hypocalcemia, not a symptom to be addressed with mouth care. Offering mouth care would not address the underlying physiological issue, which is a potential disturbance in calcium levels due to accidental removal of or damage to the parathyroid glands during thyroidectomy, a serious and life-threatening complication.
Choice B rationale
Assessing for orientation would be an inappropriate action because the patient's symptoms are physical, not neurological, and do not suggest a change in mental status. The numbness and tingling are a specific finding pointing to a possible parathyroid gland injury and subsequent hypocalcemia. The nurse must prioritize assessment and intervention related to this critical electrolyte imbalance.
Choice C rationale
Muscle twitching, or neuromuscular excitability, is a hallmark sign of severe hypocalcemia. The numbness and tingling around the mouth are early indicators, and checking for muscle twitching, such as Chvostek's or Trousseau's sign, would further confirm the suspected diagnosis. This assessment is a critical and immediate step to evaluate the severity of the electrolyte imbalance and guide appropriate intervention.
Choice D rationale
Loosening the dressing is an action for a patient experiencing symptoms of a hematoma or airway compression, such as difficulty breathing or swelling. The patient's symptom of perioral paresthesia is related to a metabolic disturbance (hypocalcemia) and is not a sign of physical compression. Therefore, loosening the dressing would not alleviate this symptom and is an incorrect intervention.
Correct Answer is A
Explanation
Choice A rationale
Brushing teeth with a soft toothbrush is crucial for a patient with stomatitis. Stomatitis, or inflammation of the oral mucosa, makes the mouth sensitive and prone to bleeding. A soft toothbrush minimizes mechanical irritation and trauma to the inflamed tissues, helping to prevent further injury and promoting healing. It allows for effective oral hygiene without exacerbating the patient's discomfort.
Choice B rationale
Rinsing with a commercial mouthwash is not recommended. Many commercial mouthwashes contain alcohol or other irritants that can cause a burning sensation and further irritate the inflamed oral mucosa, worsening the symptoms of stomatitis. They can also dry out the oral tissues. The patient should use a non-irritating, alcohol-free oral rinse, such as a saline solution or a prescribed rinse.
Choice C rationale
Toothpaste that contains sodium lauryl sulfate (SLS) is not recommended. SLS is a common foaming agent that can be irritating to sensitive oral tissues. It can contribute to mucosal dryness and breakdown, which would be detrimental for a patient with stomatitis. Patients should be advised to use a toothpaste that is free of SLS and other harsh chemicals to avoid aggravating their condition.
Choice D rationale
Cleansing the mouth with lemon-glycerine swabs is contraindicated. Lemon is acidic and can erode tooth enamel and irritate already inflamed oral tissues. Glycerine is a humectant that can pull moisture from the oral mucosa, leading to dryness. The use of these swabs has been shown to be harmful and is not an appropriate oral care practice for a patient with stomatitis.
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