What is the absolute neutrophil count (ANC) for a patient with the following lab values: WBCs of 3,000 with 30% segmented neutrophils and 25% banded neutrophils?

Enter the numeric value only.

A. Hydration is essential because dehydration increases blood viscosity, promoting sickling of red blood cells and vaso-occlusion. Parents should be instructed to encourage regular fluid intake throughout the day, even when the child does not feel thirsty. Proper hydration helps prevent painful crises and reduces the risk of organ damage.

B. Children with SCA are at increased risk for infections due to functional asplenia. Immunizations are essential to prevent serious infections, such as pneumococcal and meningococcal disease. Avoiding vaccines would increase infection risk.

C. Physical activity should be encouraged but with caution. Children should avoid extreme exertion or high-altitude activities that could lead to hypoxia, dehydration, or fatigue, which can precipitate sickle-cell crises.

D. While mild symptomatic relief may be appropriate, children with SCA require prompt evaluation for infections, particularly fevers, because even minor infections can trigger complications. Self-treatment without medical guidance may delay critical interventions.

A. Infants with congenital hypothyroidism usually present with hypotonia, not hypertonia. Muscle weakness and poor muscle tone are typical findings due to reduced metabolic activity. Hypertonia would not support a diagnosis of congenital hypothyroidism.

B. Congenital hypothyroidism typically causes bradycardia or a slow heart rate due to decreased metabolic rate. Tachycardia is more commonly associated with hyperthyroidism, fever, or other stress conditions.

C. Infants with congenital hypothyroidism often have cool, dry, and pale skin due to reduced metabolism and poor perfusion. Warm, flushed skin would be inconsistent with this diagnosis.

D. This is a classic sign of congenital hypothyroidism. Hypothyroidism slows gastrointestinal motility, leading to constipation, poor feeding, and sometimes abdominal distension. Other supportive findings include prolonged jaundice, large tongue (macroglossia), puffy face, hypotonia, poor growth, and an open posterior fontanel (delayed closure).