What is the function of lysozyme found in tear secretions?
It buffers tear pH to maintain ocular surface stability
It breaks down bacterial cell walls to prevent infection
It increases tear viscosity to improve lubrication
It stimulates tear production from the lacrimal gland
The Correct Answer is B
Tear fluid is a protective secretion produced by the lacrimal apparatus that maintains the health of the ocular surface. It is composed of water, electrolytes, mucins, lipids, and several antimicrobial substances. Among these components, lysozyme is a key innate immune enzyme that helps defend the eye against microbial invasion. Its presence is essential because the cornea is avascular and relies heavily on tears for immune protection.
A. It buffers tear pH to maintain ocular surface stability: lysozyme does not function as a pH buffer. Tear pH is primarily maintained by bicarbonate ions and other buffering systems within the aqueous component of tears. These systems help stabilize the ocular environment for optimal enzyme activity and epithelial cell function. Lysozyme instead plays a direct antimicrobial role by targeting bacterial structures, not acid-base balance.
B. It breaks down bacterial cell walls to prevent infection: lysozyme is an antibacterial enzyme that hydrolyzes peptidoglycan, a key structural component of bacterial cell walls, especially in gram-positive organisms. By breaking the β(1→4) glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine, it weakens bacterial cell integrity, leading to osmotic lysis. This enzymatic activity provides a first-line defense mechanism on the ocular surface. It is a crucial component of innate immunity in tear secretions.
C. It increases tear viscosity to improve lubrication: tear viscosity is primarily regulated by mucins secreted by goblet cells in the conjunctiva. These glycoproteins help stabilize the tear film and enhance lubrication across the corneal surface. Lysozyme does not contribute to the physical properties of tear consistency. Its role is enzymatic defense rather than lubrication or mechanical stabilization.
D. It stimulates tear production from the lacrimal gland: tear production is controlled by neural stimulation of the lacrimal gland, primarily through parasympathetic fibers of the facial nerve (cranial nerve VII). Reflex pathways triggered by irritation or emotional stimuli activate secretion. Lysozyme is not a signaling molecule and does not regulate lacrimal gland activity. Instead, it is a component released within the tears produced by the gland.
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Related Questions
Correct Answer is C
Explanation
The marked structure is the goblet cell, a specialized unicellular gland found within epithelial linings, particularly in the respiratory and gastrointestinal tracts. It is characterized by its distinctive “goblet” or flask shape, with a narrow base and a widened apical portion filled with mucin granules. Goblet cells secrete mucous, which forms a protective and lubricating layer over epithelial surfaces. This mucus traps pathogens and particulate matter in the airways and facilitates smooth passage of material in the intestines.
A. Basal cell: Basal cells are stem-like epithelial cells located in the deepest layer of stratified epithelia. They are responsible for regeneration and replacement of epithelial cells. Unlike goblet cells, they are not secretory cells and do not contain mucin-filled cytoplasm. Their main function is proliferation rather than secretion.
B. Ciliated epithelial cell: Ciliated epithelial cells possess hair-like projections called cilia on their apical surface. These cilia beat in coordinated waves to move mucus or fluid across epithelial surfaces, such as in the respiratory tract or fallopian tubes. Unlike goblet cells, they are specialized for movement rather than mucus production.
C. Goblet cell: Goblet cells are unicellular exocrine glands embedded within columnar epithelium. They produce and secrete mucin, which hydrates to form mucus that protects epithelial surfaces from mechanical damage, pathogens, and dehydration. Their characteristic shape, narrow base with a swollen mucus-filled apex, makes them easily identifiable and functionally specialized for secretion.
D. Squamous epithelial cell: Squamous epithelial cells are flat, thin cells that form the outermost layer of many epithelia. They are primarily adapted for diffusion and protective lining rather than secretion. Unlike goblet cells, they lack mucin granules and are not specialized for mucus production.
Correct Answer is D
Explanation
The eye is composed of the eyeball and several accessory structures that support its function by providing protection, lubrication, and structural maintenance. These accessory structures include the eyelids, conjunctiva, and lacrimal apparatus, which work to preserve the integrity of the ocular surface. However, they do not directly participate in the process of vision. The retina, in contrast, is part of the eyeball itself and is responsible for converting light into electrical impulses for visual processing in the brain.
A. Conjunctiva: The conjunctiva is a thin mucous membrane that lines the inner eyelids and covers the anterior sclera. It contains goblet cells that secrete mucin, contributing to tear film stability and ocular surface lubrication. It also provides immune protection by acting as a barrier against pathogens. Its role is supportive and protective rather than sensory or visual, which classifies it as an accessory structure of the eye.
B. Eyelids: The eyelids are protective anatomical structures composed of skin, muscle, and connective tissue, including the orbicularis oculi and tarsal plates. They function to shield the eye from trauma, regulate light exposure, and distribute tears evenly across the corneal surface during blinking. They also help prevent corneal drying and maintain visual clarity. They support and protect the eye rather than participate in vision, they are considered accessory structures.
C. Lacrimal apparatus: The lacrimal apparatus includes the lacrimal gland, canaliculi, lacrimal sac, and nasolacrimal duct. It is responsible for producing and draining tears that contain water, electrolytes, enzymes such as lysozyme, and immunoglobulins. These components lubricate the eye, nourish the avascular cornea, and provide antimicrobial defense. Because its function is maintenance and protection of the ocular surface rather than visual processing, it is classified as an accessory structure.
D. Retina: The retina is the innermost layer of the eyeball and is derived from neural tissue during embryological development. It contains photoreceptor cells, specifically rods and cones, which convert light energy into electrical signals through phototransduction. These signals are processed by bipolar and ganglion cells, whose axons form the optic nerve. The retina is directly responsible for initiating vision and transmitting visual information to the brain. Therefore, it is not an accessory structure but an essential component of the visual system.
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