What is the generic name of Imitrex?
Rizatriptan
Almotriptan
Sumatriptan
Eletriptan
The Correct Answer is C
A. Rizatriptan is the active pharmaceutical ingredient for the brand Maxalt. While it belongs to the same selective 5-hydroxytryptamine 1B and 1D receptor agonist class, it is not the chemical constituent of Imitrex. It possesses a different pharmacokinetic profile.
B. Almotriptan is the generic name for the brand Axert. This compound is indicated for the acute treatment of migraine with or without aura in adults. It is a separate molecular entity from the drug requested in the question stem.
C. Sumatriptan is the generic name for Imitrex, the first triptan developed for clinical use. It acts as a selective agonist at vascular 5-HT1B and 5-HT1D receptors. This binding induces cranial vessel vasoconstriction and inhibits the release of proinflammatory neuropeptides.
D. Eletriptan is marketed under the brand name Relpax. It is a second-generation triptan used for migraine abortive therapy. It is not the active ingredient in Imitrex. Its metabolism and bioavailability differ significantly from those of sumatriptan.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Tetracycline is the prototype antibiotic of the tetracycline class, originally derived from Streptomyces aureofaciens. It is a separate generic entity from doxycycline with different pharmacokinetic properties and dosing intervals. It is not the active ingredient found in the brand Vibramycin.
B. Erythromycin is a macrolide antibiotic that inhibits protein synthesis by binding to the 50S ribosomal subunit. It is used for patients with penicillin allergies but is chemically unrelated to the tetracycline family. It is not the generic name for Vibramycin.
C. Minocycline is a semi-synthetic tetracycline derivative used often for acne or specific bacterial infections. While it shares the same mechanism of action as doxycycline, it is a distinct chemical compound. It is marketed under brand names such as Minocin or Solodyn.
D. Doxycycline hyclate is the generic name for Vibramycin, a broad-spectrum tetracycline antibiotic. It functions by reversibly binding to the 30S ribosomal subunit, thereby preventing the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This action effectively inhibits bacterial protein synthesis.
Correct Answer is B
Explanation
A. Piperacillin with tazobactam is a parenteral antipseudomonal penicillin combination marketed under the brand Zosyn. It is used for severe systemic infections involving Pseudomonas aeruginosa. It is not the generic composition of the oral medication known as Augmentin.
B. Augmentin is the brand name for amoxicillin with clavulanate potassium. Amoxicillin is a beta-lactam antibiotic that inhibits cell wall synthesis. Clavulanate acts as a beta-lactamase inhibitor, preventing the enzymatic degradation of amoxicillin by resistant bacterial strains.
C. Metronidazole is a nitroimidazole antimicrobial used for anaerobic infections and protozoal diseases. It functions by creating reactive free radicals that disrupt bacterial DNA. It is a single-agent generic medication and is not the active component of Augmentin.
D. Sulfamethoxazole with trimethoprim is a sulfonamide combination marketed under the brand Bactrim or Septra. This drug inhibits two consecutive steps in the bacterial folic acid synthesis pathway. It represents a different pharmacological class than the penicillin-based Augmentin.
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