What is the generic name of Methadose?
Memantine hydrochloride
Methadone hydrochloride
Morphine sulfate
Montelukast sodium
The Correct Answer is B
A. Memantine hydrochloride functions as an N-methyl-D-aspartate receptor antagonist specifically indicated for the management of moderate to severe Alzheimer disease. It does not possess opioid receptor affinity. This pharmacological profile is entirely distinct from the therapeutic class of Methadose.
B. Methadose is a proprietary brand name for methadone hydrochloride, a synthetic mu-opioid receptor agonist. It is clinically utilized for chronic pain management and opioid detoxification programs. The chemical nomenclature directly corresponds to this specific long-acting synthetic opioid analgesic.
C. Morphine sulfate is a natural phenanthrene alkaloid derived from the opium poppy. While it shares the mu-opioid agonist mechanism, it is marketed under brand names such as MS Contin or Kadian. It is not the active moiety in Methadose.
D. Montelukast sodium is a selective leukotriene receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor. It is indicated for prophylaxis of asthma and allergic rhinitis. It lacks any structural or functional relationship to the opioid analgesic methadone.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Lidoderm is the brand name for the 5 percent transdermal patch containing lidocaine. It functions as a local anesthetic by blocking voltage-gated sodium channels in neuronal membranes. This stabilizes the membrane and inhibits the initiation and conduction of nociceptive nerve impulses.
B. Actos is the proprietary brand name for pioglitazone, a thiazolidinedione used in type 2 diabetes mellitus. It acts as an agonist for the peroxisome proliferator-activated receptor gamma to improve insulin sensitivity. It is pharmacologically unrelated to transdermal lidocaine preparations.
C. Lithobid is the brand name for a slow-release formulation of lithium carbonate. It is used primarily as a mood stabilizer in the management of bipolar disorder. It modulates neurotransmission via various intracellular signaling pathways and is not a local anesthetic.
D. Dilantin is the brand name for phenytoin, a hydantoin derivative used as an antiepileptic medication. It stabilizes neuronal membranes by promoting sodium efflux or decreasing sodium influx during generation of nerve impulses. It is not the brand name for lidocaine.
Correct Answer is A
Explanation
A. Fentanyl is a potent mu-opioid receptor agonist indicated for the management of chronic, severe pain. The transdermal system provides continuous systemic delivery of the drug over 72 hours. It is reserved for opioid-tolerant patients requiring around-the-clock long-term opioid treatment.
B. This agent does not possess sympathomimetic activity or alpha-adrenergic agonist properties required to reduce nasal mucosal swelling. It lacks the pharmacological profile of a decongestant like pseudoephedrine. It is not indicated or used for the management of congestion.
C. Fentanyl has no therapeutic effect on the inflammatory or histaminergic pathways associated with allergic rhinitis. It does not act as an H1-receptor antagonist or a nasal corticosteroid. It is not a clinical intervention for seasonal or perennial allergies.
D. Opioid analgesics do not inhibit the hypothalamic thermoregulatory center through the suppression of prostaglandin E2 synthesis. Fentanyl lacks the antipyretic properties found in cyclooxygenase inhibitors like acetaminophen or ibuprofen. It is never indicated for the management of fever.
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