When administering an alpha-adrenergic drug for hypertension, it is most important for the nurse to assess the patient for the development of what response?

Choice A rationale

Furosemide is a loop diuretic that inhibits the reabsorption of sodium and chloride in the thick ascending limb of the loop of Henle. This action increases the excretion of these ions, as well as potassium, through the kidneys. The increased urinary potassium loss can lead to hypokalemia, a common and potentially dangerous side effect requiring careful monitoring of serum potassium levels (normal range 3.5-5.0 mEq/L).

Choice B rationale

Spironolactone is a potassium-sparing diuretic that acts as a competitive antagonist of aldosterone in the distal convoluted tubule and collecting duct. By blocking aldosterone's effects, it promotes the excretion of sodium and water while promoting the reabsorption of potassium. This mechanism increases serum potassium levels, and therefore, this medication is more likely to cause hyperkalemia, not hypokalemia.

Choice C rationale

Lisinopril is an ACE inhibitor (angiotensin-converting enzyme inhibitor). It blocks the conversion of angiotensin I to angiotensin II, leading to decreased aldosterone secretion. Decreased aldosterone reduces the retention of sodium and water and the excretion of potassium. Therefore, lisinopril is more likely to cause hyperkalemia rather than hypokalemia, making it an unlikely cause.

Choice D rationale

Metoprolol is a beta-blocker that works by blocking the effects of catecholamines on beta-adrenergic receptors. It primarily affects the heart by slowing the heart rate and reducing contractility, thereby lowering blood pressure. It does not directly impact the renal tubules or the handling of potassium, so it is not a direct cause of hypokalemia. Its effect on potassium is considered negligible.

Choice A rationale

Administering a medication when there is a strong possibility the patient has already received it could lead to an overdose. The automated dispensing machine's record indicates removal of the dose, and the patient's statement, despite her confusion, suggests she might have taken it. The nurse's primary responsibility is patient safety and preventing medication errors, which this action would violate.

Choice B rationale

This is the safest course of action. The medication was removed from the machine, and the patient states she thinks she took it. The night shift nurse's failure to sign the MAR is a documentation error, but the potential for a double dose is a serious safety concern. The nurse should hold the dose and investigate further before administering anything to prevent an iatrogenic event.

Choice C rationale

Notifying the provider for a new order is an unnecessary and premature step. The issue is not that the medication is unavailable or the order is incorrect. The immediate concern is whether the patient has already received the dose. Holding the medication and verifying the administration is the correct first step, and the provider would not be contacted unless there was a clinical reason to do so, such as if the blood glucose became dangerously high.

Choice D rationale

Giving the insulin and then monitoring the patient is dangerous. Administering an additional dose of insulin could cause a severe hypoglycemic event, especially in a confused patient. The blood glucose of 142 mg/dL is not critically high, so there is no immediate need for the insulin, and the risk of a medication error outweighs any perceived benefit of administering the medication immediately.