When caring for a client with an upper respiratory infection (URI), the nurse is notified the client is taking guaifenesin (Mucinex). What is the mechanism of action of guaifenesin (Mucinex)?

Stimulate alpha-adrenergic receptors, thus producing vascular constriction of capillaries in nasal mucosa

Compete with histamine for receptor sites, thus preventing a histamine response and overall congestion.

Treat allergic rhinitis and prevent motion sickness.

Loosen bronchial secretion to assist in elimination.

Answer and Explanation

The Correct Answer is D

A. Stimulate alpha-adrenergic receptors, thus producing vascular constriction of capillaries in nasal mucosa: This describes the action of decongestants, not guaifenesin. Guaifenesin does not work by constricting blood vessels; rather, its primary function is to help manage mucus production.

B. Compete with histamine for receptor sites, thus preventing a histamine response and overall congestion: This mechanism is associated with antihistamines, which are used to relieve symptoms of allergic reactions, not with guaifenesin. Guaifenesin does not block histamine but focuses on mucus management.

C. Treat allergic rhinitis and prevent motion sickness: While these are common uses for antihistamines, they do not apply to guaifenesin. Guaifenesin is primarily an expectorant and is not indicated for treating allergic rhinitis or motion sickness.

D. Loosen bronchial secretion to assist in elimination: Guaifenesin acts as an expectorant, promoting the clearance of mucus from the airways by loosening bronchial secretions. This facilitates easier expectoration of mucus, helping to relieve chest congestion associated with upper respiratory infections.

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Correct Answer is B

Explanation

A. Stimulates effects of histamine by occupying all H receptor sites: This statement inaccurately describes the action of diphenhydramine. Instead of stimulating histamine effects, diphenhydramine actually blocks them, particularly at H1 receptors, which are involved in allergic responses.

B. Blocks effects of histamine by competing and occupying H1 receptor sites: This accurately describes the mechanism of action of diphenhydramine. As an antihistamine, it competes with histamine for binding to H1 receptor sites, effectively reducing symptoms of allergies, such as sneezing, itching, and nasal congestion.

C. Blocks effects of histamine by competing and occupying H2 receptor sites: This option is incorrect because H2 receptor antagonists are used primarily to reduce gastric acid secretion, not to treat allergic reactions. Diphenhydramine specifically targets H1 receptors, not H2 receptors.

D. Stimulates effects of histamine by increasing the amount of H2 receptor sites: This statement is also incorrect. Diphenhydramine does not stimulate histamine activity or increase receptor sites. Instead, it functions to inhibit the action of histamine at H1 receptors, which is fundamental in alleviating allergy symptoms.

A. make sure to use this each time I feel an asthma attack coming on." B. "I know that these drugs can sometimes make my heart beat faster." C. "I've heard that this drug sometimes gets less effective over time." D. "I've heard that this drug is particularly good at preventing asthma attacks during exercise."

Correct Answer is A

Explanation

A. "Make sure to use this each time I feel an asthma attack coming on": This statement indicates a need for further education. LABAs are not intended for immediate relief of acute asthma symptoms or attacks; they are designed for long-term control and prevention of symptoms. Clients should use a short-acting beta agonist (SABA) for quick relief during an asthma attack, not a LABA.

B. "I know that these drugs can sometimes make my heart beat faster": This statement reflects an understanding of a potential side effect of LABAs. Increased heart rate is a known side effect, and it is important for clients to be aware of this possibility.

C. "I've heard that this drug sometimes gets less effective over time": This statement is accurate. Tolerance can develop with LABA use, and clients should be informed about this possibility to monitor their symptoms and report any changes to their healthcare provider.

D. "I've heard that this drug is particularly good at preventing asthma attacks during exercise": This statement is correct. LABAs can be beneficial for preventing exercise-induced bronchospasm when used as part of a regular asthma management plan, and clients should understand this use.

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When caring for a client with an upper respiratory infection (URI), the nurse is notified the client is taking guaifenesin (Mucinex). What is the mechanism of action of guaifenesin (Mucinex)?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client frequently takes diphenhydramine (Benadryl) to alleviate his upper respiratory symptoms associated with allergies. Which of the following mechanism of actions applies to diphenhydramine (Benadryl)?

Correct Answer is B

Explanation

A client's severe asthma has necessitated the use of a long-acting beta2-agonist (LABA). Which of the client's statements suggests a need for further education?

Correct Answer is A

Explanation

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When caring for a client with an upper respiratory infection (URI), the nurse is notified the client is taking guaifenesin (Mucinex). What is the mechanism of action of guaifenesin (Mucinex)?

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